Evidence map›Paper›PMID 35035746›Full record

ArticleAmerican journal of translational research2021

Effect of probiotics and dietary fiber combined with pinaverium bromide on intestinal flora in patients with irritable bowel syndrome.

Han Sun, Xueting Li, Weixu Chen, Fangyuan Jia, Jing Su, Bao Zhang, Xia Wu, Ping Wu

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Han SunDepartment of Gastroenterology, Xuzhou Central Hospital Xuzhou, China.
Xueting LiDepartment of Gastroenterology, Xuzhou Central Hospital Xuzhou, China.
Weixu ChenDepartment of Gastroenterology, Xuzhou Central Hospital Xuzhou, China.
Fangyuan JiaDepartment of Gastroenterology, Xuzhou Central Hospital Xuzhou, China.
Jing SuDepartment of Gastroenterology, Xuzhou Central Hospital Xuzhou, China.
Bao ZhangDepartment of Gastroenterology, Xuzhou Central Hospital Xuzhou, China.
Xia WuDepartment of Gastroenterology, Xuzhou Central Hospital Xuzhou, China.
Ping WuDepartment of Gastroenterology, Xuzhou Central Hospital Xuzhou, China.
Xuzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the clinical efficacy of probiotics and dietary fiber combined with pinaverium bromide in the treatment of irritable bowel syndrome (IBS) and its effect on intestinal flora.

methodsAs a prospective study, 180 patients with IBS hospitalized in the gastroenterology department of our hospital from January 2018 to January 2021 were selected and assigned to Group A, Group B, or Group C using the random number table method, with 60 cases in each group. Patients in Group A received conventional treatment with pinaverium bromide tablets. Those in Group B were given bifid triple viable combined with pinaverium bromide, and those in Group C were given bifid triple viable and dietary fiber combined with pinaverium bromide. The treatment spanned 4 weeks. The treatment efficacy, degree of symptom improvement, quality of life, adverse effects, and changes in intestinal flora were compared among the three groups.

resultsThe total treatment efficacy was significantly higher in Group C compared with Group A (χ

conclusionIn patients with IBS, treatment with probiotics and dietary fiber combined with pinaverium bromide can significantly improve clinical efficacy, shorten symptom resolution time, reduce calprotectin, and regulate intestinal flora.

Indexed as

dietary fiberintestinal floraIrritable bowel syndromepinaverium bromideprobiotics

Identifiers

PMID35035746
PMCPMC8748111
OpenAlexW4206875419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.