Evidence map›Paper›PMID 35035717›Full record

ArticleAmerican journal of translational research2021

Correlation analysis of survivin, ING4, CXCL8 and VEGF expression in prostate cancer tissue.

Lingwei Kong, Rushan Qi, Guangchun Zhou, Sentai Ding

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lingwei KongDepartment of Urology, Chengwu People's Hospital Chengwu County, Heze 274200, Shandong Province, China.
Rushan QiDepartment of Urology, The First People's Hospital of Taian Taian, Shandong Province, China.
Guangchun ZhouDepartment of Urology, Chengwu People's Hospital Chengwu County, Heze 274200, Shandong Province, China.
Sentai DingDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University Jinan 250021, Shandong Province, China.
Dawu County People's Hospital · CNShandong University · CNTaizhou First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate the expression of Survivin, inhibitor of growth 4 (ING4), CXC chemokine ligand 8 (CXCL8), vascular endothelial growth factor (VEGF), and the correlation between Survivin, ING4, CXCL8 and VEGF in prostate cancer (PCa) tissues.

methodsFrom January 2019 to December 2019, 51 patients from Chengwu People's Hospital and The First People's Hospital of Taian, with PCa were selected as the PCa group and 47 patients with benign prostatic hyperplasia (BPH) were included as the BPH group. The expression of Survivin, ING4, CXCL8 and VEGF in both groups and among patients with different clinical stages in the PCa group were compared, and the correlation between Survivin, ING4, CXCL8 and VEGF expression in PCa tissues was analyzed.

resultsSurvivin, ING4, CXCL8, and VEGF expression differed significantly between the two groups (

conclusionSurvivin, CXCL8, and VEGF were highly expressed and ING4 was lowly expressed in PCa tissues, which was correlated with clinical stage; additionally, Survivin, ING4, CXCL8, and VEGF played a synergistic role with each other in the development and progression of PCa.

Indexed as

CXC chemokine ligand 8growth inhibitory factorProstate cancersurvivinvascular endothelial growth factor

Identifiers

PMID35035717
PMCPMC8748150
OpenAlexW4206893849

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.