ArticleAmerican journal of translational research2021
Ultrasound-guided microwave ablation of benign thyroid nodules: effects on inflammatory factors and thyroid function.
Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.
- Quality of Life Following Thermal Ablation of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis.Thyroid : official journal of the American Thyroid Association · 2025Pooled it
- Ultrasound-Guided Microwave Ablation for Benign Thyroid Nodules in Older Adults: Comparative Analysis of Clinical Outcomes and Safety.Diagnostics (Basel, Switzerland) · 2026Article
- Comparison of thyroid-specific quality of life after thermal ablation vs. thyroid lobectomy for benign thyroid nodules.BMC endocrine disorders · 2026Article
- Article
- Thermal Ablation as a Non-Surgical Alternative for Thyroid Nodules: A Review of Current Evidence.Medicina (Kaunas, Lithuania) · 2025Review
- Impact of real-time contrast-enhanced ultrasound on thyroid function in microwave ablation treatment of thyroid tumors.American journal of cancer research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the effects of ultrasound-guided microwave ablation on inflammatory factors and thyroid function in patients with benign thyroid nodules.
methodsA total of 150 patients with benign thyroid nodules treated in the Huazhong University of Science and Technology Union Shenzhen Hospital from January 2017 to December 2018 were selected as research participants, with 75 patients in each group. Patients in the control group received traditional surgery, while those in the study group were treated with ultrasound-guided percutaneous microwave ablation. The two groups were compared in terms of the following: clinical effect, quality of life scores, white blood cell count (WBC), hypersensitive-C-reactive-protein (hsCRP), tumor necrosis factor α (TNF-α), interleukin (IL)-6, epinephrine (E), norepinephrine (NE), visual analogue scale (VAS) scores, and serum levels of thyroid stimulating hormone (TSH), FT3, FT4, and TT4.
resultsThe total effective rate of the study group was significantly higher than that of the control group (96.00% vs. 77.33%). Before operation, there was no significant difference in WBC, VAS score, or the levels of hs-CRP, TNF-α, IL-6, E, and NE between the two groups (all P>0.05); After operation, WBC, and the levels of hs-CRP, TNF-α, IL-6, E, and NE increased significantly in both groups and were lower in the study group (all P<0.05). The nodule volume in the study group decreased with time. The serum levels of TSH, FT3, FT4, and TT4 in the study group were better than those in the control group (P<0.05). The study group obtained a lower incidence of postoperative complications than the control group (4.00% vs. 14.00%). In addition, the cosmetic score was higher and the symptom score was lower in the study group compared with the control group (all P<0.05).
conclusionIn patients with benign thyroid nodules, the ultrasound-guided microwave ablation could effectively reduce nodule volume, preserve thyroid function, and improve the quality of patients' daily life. This is closely related to a reduced inflammatory response.
Indexed as
Identifiers
35035710PMC8748158W4206865435What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.