Evidence map›Paper›PMID 35035691›Full record

ArticleAmerican journal of translational research2021

Clinical outcome of phacoemulsification combined with intraocular lens implantation for primary angle closure/glaucoma (PAC/PACG) with cataract.

Yuan He, Ruixue Zhang, Chuntao Zhang, Jun Jia, Huifeng Liu, Beilei He, Zhuoya Quan, Jian Zhang

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yuan HeDepartment of Ophthalmology, The Second Affiliated Hospital of Xi'an Medical University Xi'an 710038, Shaanxi, China.
Ruixue ZhangDepartment of Ophthalmology, The Second Affiliated Hospital of Xi'an Medical University Xi'an 710038, Shaanxi, China.
Chuntao ZhangDepartment of Ophthalmology, The Second Affiliated Hospital of Xi'an Medical University Xi'an 710038, Shaanxi, China.
Jun JiaDepartment of Ophthalmology, The Second Affiliated Hospital of Xi'an Medical University Xi'an 710038, Shaanxi, China.
Huifeng LiuDepartment of Ophthalmology, The Second Affiliated Hospital of Xi'an Medical University Xi'an 710038, Shaanxi, China.
Beilei HeDepartment of Ophthalmology, The Second Affiliated Hospital of Xi'an Medical University Xi'an 710038, Shaanxi, China.
Zhuoya QuanDepartment of Ophthalmology, The Second Affiliated Hospital of Xi'an Medical University Xi'an 710038, Shaanxi, China.
Jian ZhangShannxi Provincial People's Hospital Xi'an 710038, Shaanxi, China.
Xi'an Medical University · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the efficacy of phacoemulsification (Phaco) combined with intraocular lens implantation for treatment of primary angle-closure glaucoma (PACG) patients with cataract.

methodsA total of 62 patients treated in our hospital meeting the inclusion criteria were included, including 62 eyes (26 PAC eyes and 36 PACG eyes). PACG patients were divided into early, middle, and advanced stages based on the HPA visual field staging system. The subjects were also grouped according to the extent of peripheral anterior synechia (PAS). Patients received topical medical treatment preoperatively and Phaco performed by the same surgeon. The visual acuity, intraocular pressure (IOP), anterior chamber depth (ACD), medication used, visual field and retinal nerve fiber layer (RNFL) were observed before and 6-24 months after surgery.

resultsThe mean age of the patients was 68±8.91 years old, and postoperative follow-up was 13.1±5.5 months. Postoperative visual acuity was improved in all patients (P<0.001). Postoperatively, the IOP decreased significantly (P<0.001), the number of medications was reduced (P<0.001), and the ACD was deeper than that before operation (P<0.001). There was no significant difference in visual field (P=0.973) or RNFL (P=0.268) after surgery during the follow-up. There was no statistical difference in postoperative changes of various indexes between PAC and PACG patients. The decrease of IOP in patients with early stage PACG was significantly higher than that in patients in the middle and advanced stages (F=3.519, P=0.041), and the number of medications used in early-stage PACG patients was also significantly lower than that of advanced patients (P=0.020). There was no significant difference in postoperative visual acuity (X

conclusionIn PAC/PACG patients, Phaco can significantly control IOP, and prevent visual field defect and progressive loss of RNFL, indicating that the procedure has a protective effect on the optic nerve. Phaco is more effective in the treatment of early stage PACG than in middle or advanced stage, and can be used in PAC/PACG patients with different extents of PAS, but close follow-up is necessary.

Indexed as

cataractintraocular pressureoptic nervePhacoemulsificationprimary angle-closure glaucoma

Identifiers

PMID35035691
PMCPMC8748130
OpenAlexW4206871389

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.