ArticleOxidative medicine and cellular longevity2022
Calycosin Alleviates Doxorubicin-Induced Cardiotoxicity and Pyroptosis by Inhibiting NLRP3 Inflammasome Activation.
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Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
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Who cites it
33 citing papers in PubMed, 44 citations in OpenAlex.
- Calycosin Safeguards Mitochondrial Genomic Stability and Iron Homeostasis via the NRF2/NRF1-TFAM Axis to Mitigate Doxorubicin-Induced Cardiotoxicity.Antioxidants (Basel, Switzerland) · 2026Article
- Calycosin protects against post-myocardial infarction heart failure by activating the NRF2/HO-1 signaling pathway.Journal of thoracic disease · 2026Article
- Natural bioactive molecules and chemotherapeutics synergism for enhanced cancer therapy.Nutrition & metabolism · 2026Review
- Doxorubicin-Induced Cardiac Remodeling: Mechanisms and Mitigation Strategies.Cardiovascular drugs and therapy · 2026Review
- Combined Nivolumab and Ipilimumab Therapy Promotes Immune-Mediated Cardiomyocyte Apoptosis Through TLR4-Myd88-NF-Human mutation · 2026Article
- Calycosin attenuates mitochondrial damage and pyroptosis in heart failure via the Nrf2/ROS/TXNIP pathway.International journal of molecular medicine · 2025Article
- Emerging Role of Calycosin in Inflammatory Diseases: Molecular Mechanisms and Potential Therapeutic Applications.Biomolecules · 2025Review
- Neuropharmacological effects of calycosin: a translational review of molecular mechanisms and therapeutic applications.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Targeting the NLRP3 by Natural Compounds: Therapeutic Strategies to Mitigate Doxorubicin-Induced Cardiotoxicity.Cell biochemistry and biophysics · 2025Review
- NLRP3 inflammasome: structure, mechanism, drug-induced organ toxicity, therapeutic strategies, and future perspectives.RSC medicinal chemistry · 2025Review
- Natural products targeting regulated cell deaths for adriamycin-induced cardiotoxicity.Cell death discovery · 2025Review
- Thiolutin Alleviates Cardiotoxic Effects of Doxorubicin by Suppressing NLRP3 Inflammasome in the Mouse Model.Cardiovascular toxicology · 2025Article
- Unveiling the Complexities: Exploring Mechanisms of Anthracyclineinduced Cardiotoxicity.Current cardiology reviews · 2025Review
- NLRP3 inflammasome as a therapeutic target in doxorubicin-induced cardiotoxicity: role of phytochemicals.Frontiers in pharmacology · 2025Review
- Natural Products From Traditional Chinese Medicine: Potential Therapeutic Agents in Cancer Therapy-Induced Cardiotoxicity.Drug design, development and therapy · 2025Review
- The regulatory effects of luteolin, calycosin, and formononetin on the NLRP3/IL-33/ILC2s axis in the treatment of allergic rhinitis: mechanistic analysis and therapeutic potential.Frontiers in pharmacology · 2025Review
- Inflammation in Chemotherapy-Induced Cardiotoxicity.Current cardiology reports · 2024Review
- CTRP5 Attenuates Doxorubicin-Induced Cardiotoxicity Via Inhibiting TLR4/NLRP3 Signaling.Cardiovascular drugs and therapy · 2024Article
- The mechanism and therapeutic strategies in doxorubicin-induced cardiotoxicity: Role of programmed cell death.Cell stress & chaperones · 2024Review
- Potential of Natural Phenolic Compounds against Doxorubicin-Induced Chemobrain: Biological and Molecular Mechanisms Involved.Antioxidants (Basel, Switzerland) · 2024Review
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Lei ZhangFirst Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250000, China.ORCID https://orcid.org/0000-0003-3915-6769
Cundong FanDepartment of Neurology, Key Lab of Cerebral Microcirculation in Universities of Shandong, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong 271000, China.ORCID https://orcid.org/0000-0003-4485-1344
Hua-Chen JiaoCardiovascular Department, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250000, China.ORCID https://orcid.org/0000-0002-6830-4903
Qian ZhangFirst Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250000, China.ORCID https://orcid.org/0000-0003-0664-5654
Yue-Hua JiangFirst Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250000, China.ORCID https://orcid.org/0000-0003-0156-0715
Jie CuiDepartment of Neurology, Key Lab of Cerebral Microcirculation in Universities of Shandong, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong 271000, China.
Yang LiuICU, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250000, China.ORCID https://orcid.org/0000-0002-5414-7185
Yong-Hao JiangCardiovascular Department, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250000, China.ORCID https://orcid.org/0000-0002-5220-4027
Juan ZhangFirst Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250000, China.ORCID https://orcid.org/0000-0002-6992-5322
Meng-Qi YangFirst Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250000, China.ORCID https://orcid.org/0000-0002-2161-1973
Yan LiCardiovascular Department, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250000, China.ORCID https://orcid.org/0000-0002-5846-7813
Yi-Tao XueCardiovascular Department, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250000, China.ORCID https://orcid.org/0000-0002-6925-2519
Shandong University of Traditional Chinese Medicine · CNShandong First Medical University · CNAffiliated Hospital of Shandong University of Traditional Chinese Medicine · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
Calycosin (CAL) is the main active component present in
Indexed as
AnimalsCardiotoxicityDisease Models, AnimalDoxorubicinDrugs, Chinese HerbalHumansInflammasomesIsoflavonesMaleMiceNLR Family, Pyrin Domain-Containing 3 ProteinPyroptosis7,3'-dihydroxy-4'-methoxyisoflavoneDoxorubicinDrugs, Chinese HerbalInflammasomesIsoflavonesNLR Family, Pyrin Domain-Containing 3 Protein
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.