Evidence map›Paper›PMID 35035643›Full record

ArticleCanadian respiratory journal2022

Identification of RAGE and OSM as New Prognosis Biomarkers of Severe Pneumonia.

Jing Lei, Li Wang, Qian Li, Lin Gao, Jing Zhang, Yan Tan

Open access · goldAbstract read
In one paragraph

Article in Canadian respiratory journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jing LeiDepartment of Respiratory and Critical Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing 210000, China.
Li WangDepartment of Respiratory and Critical Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing 210000, China.
Qian LiDepartment of Respiratory and Critical Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing 210000, China.
Lin GaoDepartment of Respiratory and Critical Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing 210000, China.
Jing ZhangDepartment of Respiratory and Critical Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing 210000, China.
Yan TanDepartment of Respiratory and Critical Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing 210000, China.ORCID 0000-0002-9709-874X
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate efficiency of RAGE and OSM as new prognosis biomarkers of severe pneumonia. Methods: Eligible patients were classified into hypoxemia and nonhypoxemia groups. Meanwhile, the same cohort was divided into survival and nonsurvival groups after a post-hospital stay of 30 days. We analyzed risk factors for the hypoxia and death among these patients. Results: Compared with nonsurvival group, significant increase was noticed in PH, lymphocyte, albumin and platelet level in survival group, while significant decline was noticed in neutrophils, RBC, hemoglobin, hematocrit, creatinine, total bilirubin, CRP, PCT, OSM, RAGE and neutrophils/lymphocyte level. Oxygenation index level was related to APACHE II, LIS, SOFA, NUTRIC score, WBC, neutrophils, lymphocyte, RAGE, and albumin level ( Conclusions: RAGE and OSM may serve as a new biomarker for poor prognosis in pneumonia patients.

Indexed as

PneumoniaSepsisAntigens, NeoplasmAPACHEBiomarkersHumansMitogen-Activated Protein KinasesOncostatin MPrognosisRetrospective StudiesROC CurveAntigens, NeoplasmBiomarkersMitogen-Activated Protein KinasesMOK protein, humanOncostatin MOSM protein, human

Identifiers

PMID35035643
PMCPMC8759921
OpenAlexW4225637070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.