Evidence map›Paper›PMID 35035523›Full record

ArticleComputational and mathematical methods in medicine2022

Antibacterial and Antioxidant Effects of Magnesium Alloy on Titanium Dental Implants.

Yang Bai, Lin Wang, Lisheng Zhao, E Lingling, Shuo Yang, Shunyi Jia, Ning Wen

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yang BaiDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Lin WangDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Lisheng ZhaoDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
E LinglingDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.ORCID https://orcid.org/0000-0003-1955-9851
Shuo YangDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Shunyi JiaDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Ning WenDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.ORCID https://orcid.org/0000-0002-6283-7469
Chinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn this study, a new type of dental implant by covering the surface of the titanium (Ti) implant with zinc-magnesium (Zn-Mg) alloy was designed, to study the antibacterial and antioxidant effects of Mg alloy on titanium (Ti) implants in oral implant restoration.

methodsHuman gingival fibroblasts (HGFs), S. sanguinis, and F. nucleatum bacteria were used to detect the bioactivity and antibacterial properties of Mg alloy-coated Ti implants. In addition, B6/J mice implanted with different materials were used to further detect their antibacterial and antioxidant properties.

resultsThe results showed that Mg alloy could better promote the adhesion and proliferation and improve the alkaline phosphatase (ALP) activity of HGFs, which contributed to better improved stability of implant osseointegration. In addition, Mg alloy could better inhibit the proliferation of S. sanguinis, while no significant difference was found in the proliferation of F. nucleatum between the two implants. In the mouse model, the peripheral inflammatory reaction and oxidative stress of the Mg alloy implant were significantly lower than those of the Ti alloy implant.

conclusionsZn-Mg alloy-coated Ti implants could better inhibit the growth of Gram-positive bacteria in the oral cavity, inhibit oxidative stress, and facilitate the proliferation activity of HGFs and the potential of osteoblast differentiation, thus, better increasing the stability of implant osseointegration.

Indexed as

Dental ImplantsTitaniumAlloysAnimalsAnti-Bacterial AgentsAntioxidantsCell DifferentiationCell ProliferationCells, CulturedCoated Materials, BiocompatibleComputational BiologyDental Prosthesis DesignGingivaHumansMagnesiumMaleAlloysAnti-Bacterial AgentsAntioxidantsCoated Materials, BiocompatibleDental ImplantsMagnesiumTitaniumZinc

Identifiers

PMID35035523
PMCPMC8758302
OpenAlexW4205296378

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.