Evidence map›Paper›PMID 35035495›Full record

ArticleDrugs in context2021

Portuguese recommendations for the treatment of atopic dermatitis with biologic therapy and JAK inhibitors in adult patients.

Tiago Torres, Margarida Gonçalo, Maria João Paiva Lopes, Cristina Claro, Leonor Ramos, Manuela Selores, Pedro Mendes Bastos, Joana Rocha, Rodrigo Carvalho, Alberto Mota and 1 more

Open access · goldAbstract read
In one paragraph

Article in Drugs in context, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Clinical and economic evaluation of tralokinumab for atopic dermatitis.Journal of managed care & specialty pharmacy · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 1 country.

Tiago TorresDepartment of Dermatology, Centro Hospitalar Universitário do Porto, Porto, Portugal.
Margarida GonçaloDepartment of Dermatology, University Hospital and Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Maria João Paiva LopesDepartment of Dermatology, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.
Cristina ClaroDermatology Department, Hospital de Egas Moniz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
Leonor RamosDepartment of Dermatology, University Hospital and Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Manuela SeloresDepartment of Dermatology, Centro Hospitalar Universitário do Porto, Porto, Portugal.
Pedro Mendes BastosHospital CUF Descobertas, Lisbon, Portugal.
Joana RochaDepartment of Dermatology, Hospital de Pedro Hispano, Matosinhos, Portugal.
Rodrigo CarvalhoDepartment of Dermatology, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.
Alberto MotaDepartment of Dermatovenereology, Centro Hospitalar Universitário de São João EPE, Porto, Portugal.
Paulo FilipeDepartment of Dermatology, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal.
University of Coimbra · PTCentro Hospitalar de Lisboa Central · PTCentro Hospitalar do Porto · PTHospital CUF DescobertasHospital de Egas Moniz · PTHospital de São João · PTHospital Pedro Hispano · PTUniversidade do Porto · PTUniversidade Nova de Lisboa · PTUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis is a highly prevalent chronic, immune-mediated inflammatory skin disease with a significant burden on patients, families and healthcare systems. This article presents recommendations developed by the Atopic Dermatitis Group of the Portuguese Society of Dermatology and Venereology addressing several clinical questions that arise in the management and care of moderate-to-severe atopic dermatitis with biologic agents and Janus kinase (JAK) inhibitors based on the available evidence. The recommendations were generated after a thorough evaluation of existing guidelines on the treatment of atopic dermatitis, publications concerning new biologics and JAK inhibitors not yet incorporated into existing guidelines, and expert-based recommendations. It also includes considerations on atopic dermatitis severity, indications for initiating biologic agents and JAK inhibitors, parameters to be considered in the treatment choice, in particular treatment goals, and recommendations for the use, screening and monitoring of these therapies.

Indexed as

atopic dermatitisbiologic therapyguidelinesJAK inhibitorsrecommendationstreatment goals

Identifiers

PMID35035495
PMCPMC8722771
OpenAlexW4200322535

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.