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ArticlePakistan journal of medical sciences

Comparison of choroidal thickness in eyes of diabetic patients with eyes of healthy individuals using optical coherence tomography in a tertiary care hospital.

Hafsa Hassan, Alyscia Cheema, Muhammad Ali Tahir, Hina Nasreen Nawaz

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06272851 (Comparing the Choroidal Thickness Using Optical Coherence Tomography Between the Eyes of Healthy Individuals and Diabetic Patients Without Retinopathy), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06272851 not yet recruitingnot on this map

Comparing the Choroidal Thickness Using Optical Coherence Tomography Between the Eyes of Healthy Individuals and Diabetic Patients Without Retinopathy

TypeobservationalSponsorAssiut UniversityRan2024 to 2029Enrolled122ConditionsChoroid Disease, Diabetes MellitusArmsoptical coherence tomography
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. The Anatomic and Functional Outcomes of Ozurdex-Aided Vitrectomy in Proliferative Diabetic Retinopathy.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Hafsa HassanHafsa Hassan, MBBS, FCPS. Jinnah Post Graduate Medical Centre, Karachi, Pakistan.
Alyscia CheemaAlyscia Cheema, MBBS, FCPS, FRCS. Professor of Ophthalmology Jinnah Post Graduate Medical Centre, Karachi, Pakistan.
Muhammad Ali TahirMuhammad Ali Tahir, MBBS, FCPS (Ophthalmology), FCPS (Vitreoretina) Consultant Retinal Surgeon Jinnah Post Graduate Medical Centre, Karachi, Pakistan.
Hina Nasreen NawazHina Nasreen Nawaz, MBBS, MRCS. TRMO, Jinnah Post Graduate Medical Centre, Karachi, Pakistan.
Jinnah Postgraduate Medical Center · PKOphthalmology Associates (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the choroidal thickness in eyes of diabetic patients with eyes of age matched controls using optical coherence tomography in a tertiary care hospital.

methodsThis Cross sectional study was conducted at the Department of Ophthalmology, Jinnah Postgraduate Medical Centre Karachi, for six months from13

resultsThe average age of the patients was 39.41±15.95 years. According to our study mean central subfoveal choroidal thickness in diabetic eyes was 268.5 ± 66.22 (95% CI 240 - 297) and in non-diabetic healthy participants it was 339.3 ± 71.49 (95% CI 308 - 369) with a p-value of 0.001. However, average choroidal thickness was 261.8 ± 61.93 (95% CI 235 - 288) and 336.0 ± 74.35 (95% CI 304 - 367) in diabetic and non-diabetic healthy population with a p-value of 0.001. Choroidal thickness comparison between gender in diabetic and non-diabetic population also showed similar trend.

conclusionIn this study, mean central choroidal thickness as well as average choroidal thickness was significantly reduced in eyes having diabetic retinopathy as compared to participants with non-diabetic healthy eyes. These findings indicate that changes in choroid may be a probable route in the pathogenesis of diabetic retinopathy.

Indexed as

Choroidal thicknessDiabetic retinopathySwept source optical coherence tomography

Identifiers

PMID35035435
PMCPMC8713207
OpenAlexW3211574436

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.