Evidence map›Paper›PMID 35035423›Full record

ArticlePakistan journal of medical sciences

Comparison of cortisol levels in patients with vasovagal syncope and postural tachycardia syndrome.

Humaira Fayyaz Khan, Shazadi Ambreen, Hammad Raziq, Azmat Hayat

Open access · goldAbstract read
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Adrenocortical response during HUT test in patients with vasovagal syncope.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
    Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Humaira Fayyaz KhanDr. Humaira Fayyaz Khan, MBBS, FCPS Physiology, MHPE, Department of Physiology, Riphah International University, Islamabad, Pakistan.
Shazadi AmbreenDr. Shazadi Ambreen, MBBS, MPhil Physiology. Department of Physiology, Shifa Tameere-e-Millat University, Islamabad, Pakistan.
Hammad RaziqDr. Hammad Raziq, MBBS, MPhil Physiology. Department of Physiology, Riphah University, Islamabad, Pakistan.
Azmat HayatDr. Azmat Hayat, MRCP, FRCP. Fellow Electrophysiology, Armed Forces Institute of Cardiology, Rawalpindi, Pakistan.
Armed Forces Institute of Pathology · PKMorpho (United States) · USRiphah International University · PKShifa Tameer-e-Millat University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the levels of cortisol in patients of vasovagal syncope (VVS) and postural tachycardia syndrome (POTS).

methodsA cross-sectional analytical study was conducted at Islamic International Medical College, Rawalpindi and Electrophysiology Department at (AFIC). This study included 80 subjects, comprising of 35 patients in each group of vasovagal syncope and postural tachycardia syndrome and 10 healthy subjects. Patients with complaint of syncope was evaluated for vasovagal syncope and postural tachycardia syndrome using Head Up Tilt Test (HUTT. Blood samples of all the participants were taken and serum cortisol was analyzed using ELISA method. Results were analyzed on SPSS Statistics 21 using ANOVA with a p value of ≤0.05 regarded as significant.

resultsHormonal analysis shows that cortisol levels in the vasovagal, postural tachycardia syndrome and in control group was 153±16.7pg/ml, 160.17±pg/ml, and 69.65± 5.8pg/ml respectively. Cortisol levels were significantly higher in both vasovagal and POTS groups as compared to controls with a p-value of 0.04 and 0.023 respectively. However, there was no significant difference between vasovagal and POTS patients with p value 0.570.

conclusionIt is concluded from the study that cortisol responses of VVS and POTS were positive.

Indexed as

Head Up Tilt TestPostural Tachycardia SyndromeSerum CortisolSyncopeVasovagal Syncope

Identifiers

PMID35035423
PMCPMC8713199
OpenAlexW3213372108

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.