Evidence map›Paper›PMID 35035295›Full record

ArticleInternational journal of MS care

A Survey of Cannabis Use in a Large US-Based Cohort of People with Multiple Sclerosis.

Amber Salter, Robert J Fox, Gary Cutter, Ruth Ann Marrie, Kate E Nichol, Joshua R Steinerman, Karry M J Smith

Open access · diamondAbstract read
In one paragraph

Article in International journal of MS care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Amber SalterWashington University in St Louis, St Louis, MO, USA (AS [now at UT Southwestern Medical Center]).ORCID https://orcid.org/0000-0002-1088-110X
Robert J FoxMellen Center for Multiple Sclerosis, Cleveland Clinic, Cleveland, OH, USA (RJF).ORCID https://orcid.org/0000-0002-4263-3717
Gary CutterThe University of Alabama at Birmingham, Birmingham, AL, USA (GC).ORCID https://orcid.org/0000-0002-8455-980X
Ruth Ann MarrieMax Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada (RAM).ORCID https://orcid.org/0000-0002-1855-5595
Kate E NicholGreenwich Biosciences, Inc, Carlsbad, CA, USA (KEN, JRS, KMJS).
Joshua R SteinermanGreenwich Biosciences, Inc, Carlsbad, CA, USA (KEN, JRS, KMJS).
Karry M J SmithGreenwich Biosciences, Inc, Carlsbad, CA, USA (KEN, JRS, KMJS).ORCID https://orcid.org/0000-0002-7670-2143
Cleveland Clinic · USUniversity of Alabama at Birmingham · USUniversity of Manitoba · CAWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs cannabis products become increasingly accessible across the United States, it is important to understand the contemporary use of cannabis for managing multiple sclerosis (MS) symptoms.

methodsWe invited participants with MS from the North American Research Committee on Multiple Sclerosis (NARCOMS) Registry (aged 18 years or older) to complete a supplemental survey on cannabis use between March and April 2020. Participants reported cannabis use, treated symptoms, patterns, preferences, methods of use, and the factors limiting use. Findings are reported using descriptive statistics.

resultsOf the 6934 participants invited, 3249 responded. Of the respondents, 31% reported having ever used cannabis to treat MS symptoms, with 20% currently using cannabis. The remaining 69% had never used cannabis for MS symptoms, for reasons including not enough data about efficacy (40%) and safety (27%), and concerns about legality (25%) and cost (18%). The most common symptoms current users were attempting to treat were spasticity (80%), pain (69%), and sleep problems (61%). Ever users (vs never users) were more likely to be younger, be non-White, have lower education, reside in the Northeast and West, be unemployed, be younger at symptom onset, be currently smoking, and have higher levels of disability and MS-related symptoms (all

conclusionsDespite concerns about insufficient safety and efficacy data, legality, and cost, almost one-third of NARCOMS Registry respondents report having tried nonprescription cannabis products in an attempt to alleviate their symptoms. Given the lack of efficacy and safety data on such products, future research in this area is warranted.

Indexed as

MarijuanaMultiple sclerosis (MS)PainPrescription drug useSleepSpasticity

Identifiers

PMID35035295
PMCPMC8745229
OpenAlexW4200400311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.