Evidence map›Paper›PMID 35035211›Full record

ArticleThe Egyptian journal of neurology, psychiatry and neurosurgery2022

Case series of intravenous thrombolysis for acute ischemic stroke in confirmed COVID-19 patients: single-centre experience.

Ahmad Sulaiman Alwahdy, Ika Yulieta Margaretha, Kenyo Sembodro Pramesti, Nailaufar Hamro, Viska Yuzella, Fitriani Nasution, Arfan Mappalilu

Open access · diamondAbstract readCase Reports
In one paragraph

Article in The Egyptian journal of neurology, psychiatry and neurosurgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Recombinant tissue plasminogen activator (rTPA) management for first onset acute ischemic stroke with covid -19 and non-covid -19 patients.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Article
  2. Ischemic and Hemorrhagic Cerebrovascular Events Related to COVID-19 Coagulopathy and Hypoxemia.International journal of environmental research and public health · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ahmad Sulaiman AlwahdyDepartment of Neurology, Fatmawati Central General Hospital, Jl. RS. Fatmawati Raya No.4, RT.4/RW.9, Cilandak Barat, Kec. Cilandak, Kota Jakarta Selatan, Daerah Khusus Ibukota Jakarta, 12430 Indonesia.ORCID 0000-0002-5291-6606
Ika Yulieta MargarethaDepartment of Neurology, Fatmawati Central General Hospital, Jl. RS. Fatmawati Raya No.4, RT.4/RW.9, Cilandak Barat, Kec. Cilandak, Kota Jakarta Selatan, Daerah Khusus Ibukota Jakarta, 12430 Indonesia.
Kenyo Sembodro PramestiUniversity of UIN Syarif Hidayatullah, Tangerang, Indonesia.
Nailaufar HamroUniversity of UIN Syarif Hidayatullah, Tangerang, Indonesia.
Viska YuzellaUniversity of UIN Syarif Hidayatullah, Tangerang, Indonesia.
Fitriani NasutionDepartment of Neurology, Fatmawati Central General Hospital, Jl. RS. Fatmawati Raya No.4, RT.4/RW.9, Cilandak Barat, Kec. Cilandak, Kota Jakarta Selatan, Daerah Khusus Ibukota Jakarta, 12430 Indonesia.
Arfan MappaliluDepartment of Neurology, Fatmawati Central General Hospital, Jl. RS. Fatmawati Raya No.4, RT.4/RW.9, Cilandak Barat, Kec. Cilandak, Kota Jakarta Selatan, Daerah Khusus Ibukota Jakarta, 12430 Indonesia.
Fatmawati Hospital · IDSyarif Hidayatullah State Islamic University Jakarta · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) not only caused a large surge of respiratory infections, it also had a potential association with and increases the risk of stroke. The pandemic has certainly provided new challenges and opportunities in the management of acute ischemic stroke (AIS); however, data regarding outcomes of intravenous tissue plasminogen activator (IV TPA) administration in stroke patients with COVID-19 remains limited. CASE PRESENTATION: Three AIS patients with confirmed COVID-19 treated using IV tPA. One case had excellent outcome, while the other cases showed unfavorable results. The risk-benefit ratio of IV TPA in COVID-19 remains unclear.

conclusionIn this article, we discuss the possible explanation behind these different outcomes. Although IV tPA could not cure COVID-19, we suggest that its administration should not be delayed in AIS patients with COVID-19.

Indexed as

Case seriesCOVID-19Intravenous thrombolysisIschemic strokeRt-PA

Identifiers

PMID35035211
PMCPMC8743695
OpenAlexW4205365726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.