ArticleMedical journal, Armed Forces India2022
Prevalence of Vitamin B12 deficiency in elderly population (>60 years) presenting with dementia to outpatient department.
Article in Medical journal, Armed Forces India, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Vitamin deficiency, a neglected risk factor for post-anesthesia complications: a systematic review.European journal of medical research · 2025Pooled it
- Vitamin B12, Homocysteine and Cognitive Impairment in Elderly Patients with Type 2 Diabetes.Journal of clinical medicine · 2026Article
- Glycated hemoglobin levels and geriatric depression impact cognitive status in an Indian urban elderly community.IBRO neuroscience reports · 2025Article
- Article
- Association of the Area Deprivation Index With Dementia Basic Workup and Diagnosis in Central and Western Virginia: A Cross-Sectional Study.Neurology. Clinical practice · 2024Article
- Optimal anti-amyloid-beta therapy for Alzheimer's disease via a personalized mathematical model.PLoS computational biology · 2022Article
- Influences of Vitamin BNutrients · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVitamin B12 deficiency is an easily treatable cause of reversible dementia. It is likely to be more common in Indian population due to traditionally vegetarian culture. This study was conducted to estimate the prevalence of Vitamin B12 deficiency in elderly patients (>60 years) with dementia attending outpatient department.
methodsThis study was conducted in two phases. The first phase was a cross sectional observational study to estimate the prevalence of Vitamin B12 deficiency in the elderly population with dementia. The second phase was a pilot study done in subjects with Vitamin B12 deficiency to assess the change in cognition following Vitamin B12 supplementation.
resultsOut of 2920 study eligible subjects, 200 were diagnosed as dementia with Mini Mental Status Examination (MMSE) score of ≤ 24. Vitamin B12 deficiency was seen in 7.5% of patients. Vitamin B12 deficiency was associated with shorter and more severe dementia. Macrocytosis was more common in Vitamin B12 deficiency (
conclusionPrevalence of Vitamin B12 deficiency in dementia was 7.5%. It was associated with macrocytosis, shorter duration and more severe dementia. There was a significant improvement in median MMSE score at 6 weeks and 12 weeks following Vitamin B12 supplementation.
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