ArticleMedical science monitor : international medical journal of experimental and clinical research2022
Epidemiology of Birth Defects in Eastern China and the Associated Risk Factors.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Tooth wear prevalence in individuals with Down syndrome: a systematic review.Clinical oral investigations · 2023Pooled it
- Spatial Epidemiologic Analysis of Fetal Birth Defects in Guangxi, China.International journal of general medicine · 2025Article
- Analysis on the prevalence and temporal trends of adverse birth outcomes among neonates in Shanghai from 2010 to 2023.Frontiers in public health · 2025Article
- Chromosomal abnormalities detected by chromosomal microarray analysis and pregnancy outcomes of 4211 fetuses with high-risk prenatal indications.Scientific reports · 2024Article
- Multivariate logistic regression analysis of risk factors for birth defects: a study from population-based surveillance data.BMC public health · 2024Article
- Epidemiology of birth defects based on a birth defects surveillance system in southwestern China and the associated risk factors.Frontiers in pediatrics · 2023Article
- Birth defects data from hospital-based birth defect surveillance in Guilin, China, 2018-2020.Frontiers in public health · 2022Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND This study aimed to survey the overall situation of birth defects (BDs) among citizens of Hangzhou, China, and the risk factors of different BD types. MATERIAL AND METHODS We collected the data of 4349 perinatal infants with BDs in Hangzhou. The potentially associated risk factors of BDs were recorded and logistic regression analysis was used to predict the high incidence of BDs. RESULTS Among all perinatal infants with BDs, there were 4105 (94.3%) single births, 225 (5.2%) twin births, and 10 (0.2%) multiple births. In clinical outcomes, there were 2477 (57.0%) live births, 1806 (41.5%) dead fetuses, and 11 (0.3%) stillbirths. Down syndrome ranked first, accounting for 30.7% of the total births, followed by cleft lip and polydactyly. Low family income, nulliparity, high parity, high education level, and taking contraceptives in early pregnancy were found to be risk factors of Down syndrome. Low parity, low education level, and pesticide exposure were found to be risk factors of cleft lip. For polydactyly, young age of the mother and a parity above 0 were identified as risk factors. CONCLUSIONS Different risks factors can influence BD development and potentially help to predict specific BD types, such as demographic features and harmful exposure in early pregnancy.
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