ArticleJournal of cardiothoracic surgery2022
Left ventricle reverse remodeling in chronic aortic regurgitation patients with dilated ventricle after aortic valve replacement.
Article in Journal of cardiothoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Emergency Bentall procedure at 15 weeks' gestation for giant aortic root aneurysm in Marfan syndrome: a case report.European heart journal. Case reports · 2026Article
- Cardiac Imaging Predictors of Ventricular Recovery in Pediatric Patients Undergoing Aortic Valve Intervention for Regurgitation.Pediatric cardiology · 2026Article
- Prognostic Impact of 1-Year Left Ventricular Mass Regression After Aortic Valve Surgery in Severe Aortic Regurgitation.Korean circulation journal · 2026Article
- Hemodynamic changes and mid-term results of surgical correction of de novo aortic valve insufficiency after left ventricular assist device implantation.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025Article
- Strain assessment in patients with aortic regurgitation undergoing transcatheter aortic valve implantation: case series.European heart journal. Case reports · 2024Article
- Aortic Regurgitation: From Valvular to Myocardial Dysfunction.Journal of clinical medicine · 2024Review
- The Association Between Ascending Aortic and Left Ventricular Dimensions in Patients After Aortic Valve Replacement.Brazilian journal of cardiovascular surgery · 2024Article
- Echocardiographic assessment of aortic regurgitation: a narrative review.Echo research and practice · 2024Review
- Incidence and Risk Factors for Long-Term Persistence of Diastolic Dysfunction after Aortic Valve Replacement for Aortic Stenosis Compared with Aortic Regurgitation.Journal of cardiovascular development and disease · 2023Article
- Twenty-five year experience with aortic valve-sparing root replacement in a single teaching center.Frontiers in cardiovascular medicine · 2023Article
- Diastolic versus Systolic Left Ventricular Dysfunction as Independent Predictors for Unfavorable Postoperative Evolution in Patients with Aortic Regurgitation Undergoing Aortic Valve Replacement.Medicina (Kaunas, Lithuania) · 2022Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAortic valve replacement (AVR) for chronic aortic regurgitation (AR) with a severe dilated left ventricle and dysfunction leads to left ventricle remodeling. But there are rarely reports on the left ventricle reverse remodeling (LVRR) after AVR. This study aimed to investigate the LVRR and outcomes in chronic AR patients with severe dilated left ventricle and dysfunction after AVR.
methodsWe retrospectively analyzed the clinical datum of chronic aortic regurgitation patients who underwent isolated AVR. The LVRR was defined as an increase in left ventricular ejection fraction (LVEF) at least 10 points or a follow-up LVEF ≥ 50%, and a decrease in the indexed left ventricular end-diastolic diameter of at least 10%, or an indexed left ventricular end-diastolic diameter ≤ 33 mm/m
resultsSixty-nine patients with severe dilated left ventricle and dysfunction underwent isolated AVR. LV remodeling in 54 patients and no LV remodeling in 15 patients at 6-12 months follow-up. The preoperative left ventricular dimensions and volumes were larger, and the EF was lower in the LV no remodeling group than those in the LV remodeling group (all p < 0.05). The adverse LVRR was the predictor for MACE at follow-up. The mean follow-up period was 47.29 months (range 6 to 173 months). The rate of freedom from MACE was 94.44% at 5 years and 92.59% at 10 years in the remodeling group, 60% at 5 years, and 46.67% at 10 years in the no remodeling group.
conclusionsThe left ventricle remodeling after AVR was the important predictor for MACE. LV no remodeling may not be associated with benefits from AVR for chronic aortic regurgitation patients with severe dilated LV and dysfunction.
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