Evidence map›Paper›PMID 35034609›Full record

ArticleBMC immunology2022

Seroconversion rates following 2 doses of measles- mumps- rubella vaccination given at the ages 12 and 18 months: data for possible additional dose at older age.

Hana Saffar, Sayed Jaber Mousavi, Hiva Saffar, Mohammad-Reza Parsaei, Gholam-Reza Ghorbani, Mohammad Jafar Saffar

Open access · goldAbstract read
In one paragraph

Article in BMC immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hana SaffarDepartment of Anatomical and Clinical Pathology, IKHC, Teheran University of Medical Sciences, Tehran, Iran.
Sayed Jaber MousaviDepartment of Community Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Hiva SaffarDepartment of Pathology, Shariati Hospital, Teheran University of Medical Sciences, Tehran, Iran.
Mohammad-Reza ParsaeiDeputy of Health, Mazandaran University of Medical Sciences, Sari, Iran.
Gholam-Reza GhorbaniDeputy of Health, Mazandaran University of Medical Sciences, Sari, Iran.
Mohammad Jafar SaffarPediatric Infectious Diseases Research Center, Communicable Diseases Institute and Department of Pediatric Infectious Diseases, Bu-Ali Sina Hospital, Mazandaran University of Medical Sciences, Pasdaran Bolv, Sari, Iran. mjsaffar1400@gmail.com.
Mazandaran University of Medical Sciences · IRShariati Hospital · IRSina Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite high rate of vaccination coverage with 2-doses of measles containing vaccine among Iranian children, outbreaks of measles occurred among different age groups and fully vaccinated subjects. Although the main reason for these outbreaks is unknown, however, vaccine failure was supposed to be an important cause. This study was designed to determine the seroconversion rates to measles- mumps- rubella (MMR) vaccine currently in use among Iranian children.

methodsThis prospective study was conducted among healthy children older than 12 months who were candidates of scheduled MMR vaccination. Blood samples were obtained from each mother- infant pair just before vaccination, and from infants 4-6 weeks after MMR

resultsDuring 22-months study period, 92 mother- infant pairs were participated. Seroimmunity rates against MMR viruses were 85.8%, 84.7% and 86.9% for mothers, and 3.2%, 2.1% and 1.0% for children, respectively. After MMR

conclusionMajority of the mothers and few infants were immune to MMR viruses prior to MMR

Indexed as

MeaslesMumpsRubellaAgedAntibodies, ViralChildHumansInfantIranMeasles-Mumps-Rubella VaccineProspective StudiesSeroconversionVaccinationAntibodies, ViralMeasles-Mumps-Rubella VaccineEliminationIranMeaslesMMRMumpsPrimary vaccine failureRubellaSeroconversion rate

Identifiers

PMID35034609
PMCPMC8762940
OpenAlexW4205132902

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.