Evidence map›Paper›PMID 35034271›Full record

ArticleMolecular diversity2022

Green and four-component cyclocondensation synthesis and in silico docking of new polyfunctionalized pyrrole derivatives as the potential anticholinesterase agents.

Mohammad Hadi Meshkatalsadat, Ahmad Mahmoudi, Safa Lotfi, Behjat Pouramiri, Alireza Foroumadi

Abstract read
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In one paragraph

Article in Molecular diversity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Mohammad Hadi MeshkatalsadatDepartment of Chemistry, Faculty of Science, Qom University of Technology, 37195, Qom, Iran.
Ahmad MahmoudiDepartment of Chemistry, Shahid Bahonar University of Kerman, Kerman, Iran.
Safa LotfiDepartment of Biotechnology, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran.
Behjat PouramiriDepartment of Chemistry, Faculty of Science, Qom University of Technology, 37195, Qom, Iran. b.pouramiri.chem@gmail.com.
Alireza ForoumadiDepartment of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. aforoumadi@yahoo.com.
Qom University of Technology · IRGraduate University of Advanced Technology · IRShahid Bahonar University of Kerman · IRTehran University of Medical Sciences · IR

Funding

Qom University of Technology 12-133
6 · The paper itself

Abstract

Synthesis of new substituted pyrrole scaffolds containing substituted thiadiazol-2-amine moiety was successfully developed through one-pot and multi-component tandem condensation reaction utilizing of triethyl ammonium hydrogen sulfate ([Et3NH][HSO4]) ionic liquid as a green media under solvent-free conditions. The chemical structures of all newly synthesized compounds were fully characterized by spectroscopic methods (IR,

Indexed as

Cholinesterase InhibitorsIonic LiquidsAcetylcholinesteraseBinding SitesMolecular Docking SimulationMolecular StructurePyrrolesStructure-Activity RelationshipAcetylcholinesteraseCholinesterase InhibitorsIonic LiquidsPyrrolesAnticholinesteraseGreen synthesisMulti-component reaction (MCRs)Polyfunctionalized pyrroleSolvent-free conditions

Identifiers

PMID35034271
OpenAlexW4205758693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.