Evidence map›Paper›PMID 35034237›Full record

ArticleAIDS and behavior2022

Perceptions About Local ART Adherence Norms and Personal Adherence Behavior Among Adults Living with HIV in Rural Uganda.

Jessica M Perkins, Bernard Kakuhikire, Charles Baguma, Justin D Rasmussen, Emily N Satinsky, Allen Kiconco, Justus Kananura, Carolyn M Audet, Mark J Siedner, Jessica E Haberer and 2 more

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Jessica M PerkinsPeabody College, Vanderbilt University, PMB 90, 230 Appleton Place, Nashville, TN, 37203-5721, USA. jessica.m.perkins@vanderbilt.edu.ORCID http://orcid.org/0000-0002-5475-8816
Bernard KakuhikireMbarara University of Science and Technology, Mbarara, Uganda.
Charles BagumaMbarara University of Science and Technology, Mbarara, Uganda.
Justin D RasmussenDuke University, Durham, NC, USA.
Emily N SatinskyCenter for Global Health, Massachusetts General Hospital, Boston, MA, USA.
Allen KiconcoMbarara University of Science and Technology, Mbarara, Uganda.
Justus KananuraMbarara University of Science and Technology, Mbarara, Uganda.
Carolyn M AudetVanderbilt Institute of Global Health, Vanderbilt University Medical Center, Nashville, TN, USA.
Mark J SiednerCenter for Global Health, Massachusetts General Hospital, Boston, MA, USA.
Jessica E HabererCenter for Global Health, Massachusetts General Hospital, Boston, MA, USA.
David R BangsbergMbarara University of Science and Technology, Mbarara, Uganda.
Alexander C TsaiMbarara University of Science and Technology, Mbarara, Uganda.
Mbarara University of Science and Technology · UGHarvard University · USDuke University · USMassachusetts General Hospital · USPortland State University · USUniversity of the Witwatersrand · ZAVanderbilt University · US

Funding

Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Stephany Norah Duda · 2015 to 2026
$27.5M
Social Networks, HIV Stigma, and the HIV Care Cascade in Rural UgandaR01MH113494 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI TSAI, ALEXANDER C · 2017 to 2021
$3.2M
Perceptions of Social Norms and Personal Propensity to Engage in HIV Testing: A Mixed Methods Study and Intervention in Rural UgandaK01MH115811 · NIMH · VANDERBILT UNIVERSITY · PI PERKINS, JESSICA M · 2018 to 2022
$857k
Optimizing mHealth for adherence monitoring and interventionK24MH114732 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI HABERER, JESSICA ELIZABETH · 2017 to 2021
$800k
Foundation for the National Institutes of Health K01MH115811Foundation for the National Institutes of Health K24MH114732Foundation for the National Institutes of Health (US) R01MH113494NIAID NIH HHS P30 AI110527NIH HHS P30 AI110527NIMH NIH HHS K01 MH115811NIMH NIH HHS K24 MH114732NIMH NIH HHS R01 MH113494
6 · The paper itself

Abstract

Although misperceived norms often drive personal health behaviors, we do not know about this phenomenon in the context of antiretroviral therapy (ART) adherence. We conducted a cross-sectional study including all persons living with HIV (PLWH) on ART across eight villages in one parish in a rural region of southwestern Uganda. We used surveys to measure personal reports of ART adherence (not missing any doses of ART in the past 7 days was considered optimal adherence whereas missing doses was considered suboptimal adherence) and perceived norms about the local ART adherence norm (whether or not each individual thought 'most other PLWH on ART in this parish' missed any doses in the past 7 days). Multivariable Poisson regression models were used to estimate the association between perceived norms and personal adherence. Among 159 PLWH on ART (95% response rate), 142 (89%) reported no missed doses. However, 119 (75%) thought most individuals in this population of PLWH on ART were sub-optimally adherent. This misperception about the local ART adherence norm was prevalent in every subgroup of PLWH. Misperceiving the local ART adherence norm to be sub-optimal adherence was associated with a reduced likelihood of optimal adherence among married PLWH (adjusted relative risk [aRR] = 0.83; 95% confidence interval [CI] 0.71-0.97). The association was similar but imprecisely estimated for all PLWH (aRR = 0.91; 95% CI 0.82-1.01). Interventions to correct misperceived ART adherence norms as a stand-alone intervention or as a complement to other adherence promotion programs may influence ART adherence behavior and perhaps reduce HIV-related stigma.

Indexed as

HIV InfectionsAdultAnti-Retroviral AgentsCross-Sectional StudiesHumansMedication AdherenceSocial StigmaUgandaAnti-Retroviral AgentsAntiretroviral therapyDescriptive normsSocial networksSocial normsStigma

Identifiers

PMID35034237
PMCPMC9248068
OpenAlexW4205106933

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.