ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2022
Marital status and survival in laryngeal squamous cell carcinoma patients: a multinomial propensity scores matched study.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 9 citations in OpenAlex.
- The Construction and Validation of a new Predictive Model for Overall Survival of Clear Cell Renal Cell Carcinoma Patients with Bone Metastasis Based on Machine Learning Algorithm.Technology in cancer research & treatmentTrial
- Machine learning for survival outcome in head and neck squamous cell carcinoma: a multicenter validation study.Scientific reports · 2025Observational
- Creation of a machine learning-based prognostic prediction model for various subtypes of laryngeal cancer.Scientific reports · 2024Article
- Individualized treatment recommendations for patients with locally advanced head and neck squamous cell carcinoma utilizing deep learning.Frontiers in medicine · 2024Article
- Marital status impacts survival of stage I non-small-cell lung cancer: a propensity-score matching analysis.Future science OA · 2024Article
- Distant Metastasis Pattern and Prognostic Prediction Model of Colorectal Cancer Patients Based on Big Data Mining.Frontiers in oncology · 2022Article
- Investigating Disparities in Hypopharyngeal/Laryngeal Cancer Survival in Florida With Geospatial Mapping Analysis.Cancer control : journal of the Moffitt Cancer CenterArticle
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8 authors at 2 institutions in 1 country.
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Abstract
objectiveTo explore the correlation between the marital status and prognosis of patients with laryngeal squamous cell carcinoma (LSCC). STUDY
designMPSM was adopted to minimize the maximum standardized average difference of the covariates among the four groups with different marital status.
settingMultinomial propensity scores matching (MPSM) based on data from the surveillance, epidemiology, and end results (SEER) database.
methodsThe Kaplan-Meier method and log-rank test were used to compare the survival outcomes of these groups with different marital status.
resultsTotally, 16,981 LSCC patients (median [IQR] age 62 [55-69] years; 829 [76.41%] males) from 2004 to 2016 were included in this study. Among them, 9112 (53.66%) were married, 2708 (15.95%) divorced or separated, 1709 (10.06%) widowed, and 3452 (20.33%) single. After MPSM, the weights make the characteristics of four groups with different marital status sufficient balance. The Kaplan-Meier method and log-rank test showed widowed patients may lead to the highest mortality rate while married patients have a higher survival rate than the other three groups. Single and divorced or separated patients had no significant difference in the survival rate. In addition, multivariate analysis by controlling for confounding factors showed that in male, well-differentiated, and early stage patients, compared with married, unmarried was an independent risk factor for CSS (P < 0.05).
conclusionMarital status showed a significant association with the survival status of LSCC patients. Importantly, the outcome of married patients was better, while widowed patients tended to have worse prognosis.
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