Evidence map›Paper›PMID 35034139›Full record

ArticleCardiovascular and interventional radiology2022

Trans-Arterial Radioembolization with Yttrium-90 of Unresectable and Systemic Chemotherapy Resistant Hepatoblastoma in Three Toddlers.

Huseyin Tugsan Balli, Kairgeldy Aikimbaev, Isa Burak Guney, Ferhat Can Piskin, Begul Yagci-Kupeli, Serhan Kupeli, Turan Kanmaz

Abstract read
PubMed Publisher
In one paragraph

Article in Cardiovascular and interventional radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Intervention in the Native and Transplant Liver in Children: An Update.Cardiovascular and interventional radiology · 2025
    Review
  4. Article
  5. Tumor ablation in children.Pediatric radiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Huseyin Tugsan BalliDepartment of Radiology, Cukurova University Medical School, Balcali Hospital, Adana, Turkey.ORCID http://orcid.org/0000-0002-5324-0097
Kairgeldy AikimbaevDepartment of Radiology, Cukurova University Medical School, Balcali Hospital, Adana, Turkey.ORCID http://orcid.org/0000-0002-5436-6492
Isa Burak GuneyDepartment of Nuclear Medicine, Cukurova University Medical School, Balcali Hospital, Adana, Turkey.ORCID http://orcid.org/0000-0002-7642-9546
Ferhat Can PiskinDepartment of Radiology, Cukurova University Medical School, Balcali Hospital, Adana, Turkey. ferhatcpiskin@gmail.com.ORCID http://orcid.org/0000-0003-4092-1077
Begul Yagci-KupeliDepartment of Pediatric Hematology and Oncology, University of Health Sciences, Adana Education and Research Center, Adana, Turkey.ORCID http://orcid.org/0000-0002-1316-4501
Serhan KupeliDepartment of Pediatric Oncology, Cukurova University Medical School, Balcali Hospital, Adana, Turkey.ORCID http://orcid.org/0000-0001-7271-1803
Turan KanmazDepartment of Pediatric Surgery, Organ Transplantation Center, Koc University Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-1886-7721
Cukurova University · TRKoç University · TRSağlık Bilimleri Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this short communication was to report the results of transarterial radioembolization (TARE) with Yttrium-90 (Y90) loaded resin microspheres in three toddlers with unresectable and systemic chemotherapy-resistant HB hepatoblastoma (HB). Six TARE procedures were performed on the patients. The dose required for treatment was calculated using partition model. Administered doses of Y90 were 1.369, 0.851, and 1.147 GBq. Complete radiological response in two patients and partial response enabling liver resection in one patient were achieved. Neither life-threatening nor minor complications developed after the treatment. These results demonstrates that HB is a radiosensitive neoplasm, and TARE-Y90 can be used as the primary, neoadjuvant and palliative treatment method in patients with unresectable and systemic chemotherapy-resistant HBs. However, studies with higher number of patients and long-term results are required.

Indexed as

Carcinoma, HepatocellularEmbolization, TherapeuticHepatoblastomaLiver NeoplasmsChild, PreschoolHumansYttrium RadioisotopesYttrium-90Yttrium RadioisotopesHepatoblastoma Toddlers Transarterial Radioembolization Yttrium-90

Identifiers

PMID35034139
OpenAlexW4205604001

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.