Evidence map›Paper›PMID 35033149›Full record

ArticleJournal of orthopaedic surgery and research2022

Why the patients with Hirayama disease have abnormal cervical sagittal alignment? A radiological measurement analysis of posterior cervical extensors.

Ye Tian, Lin Xie, Jianyuan Jiang, Hongli Wang

Open access · goldAbstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ye Tian *Department of Orthopedics, Huashan Hospital, Fudan University, Spinal Center Fudan University, 12 Mid-Wulumuqi Road, Shanghai, 200040, China.
Lin Xie *Department of Orthopedics, Huashan Hospital, Fudan University, Spinal Center Fudan University, 12 Mid-Wulumuqi Road, Shanghai, 200040, China.
Jianyuan JiangDepartment of Orthopedics, Huashan Hospital, Fudan University, Spinal Center Fudan University, 12 Mid-Wulumuqi Road, Shanghai, 200040, China. 20211220061@fudan.edu.cn.
Hongli WangDepartment of Orthopedics, Huashan Hospital, Fudan University, Spinal Center Fudan University, 12 Mid-Wulumuqi Road, Shanghai, 200040, China. wanghongli@huashan.org.cn.
Huashan Hospital · CN

Funding

Clinical Research Plan of SHDC No. SHDC2020CR4030Clinical Technology Innovation Project of SHDC No. SHDC12019X26
6 · The paper itself

Abstract

purposeTo explore the relationship between the strength of posterior cervical extensors (PCEs) and cervical sagittal alignment in Hirayama disease (HD) patients.

methodsWe analyzed the (magnetic resonance imaging) MRI T2WI and X-rays of 60 HD patients who visited Huashan Hospital from June 2017 to February 2020. Symptoms of these patients include adolescent onset, manifestation of unilateral upper limb muscle weakness and muscle atrophy of the forearm and hand. MRI images were used to measure (the cross-sectional area) CSA of cervical PCEs. The ratio of muscle CSA to vertebral body areas at the same level is defined as R-CSA. Cervical sagittal alignment includes the C

resultsSpearman correlation test revealed that R-CSA negatively correlated with T1S (S = 0.34, r = 0.34, p = 0.01) and LKA (S = 0.44, r = 0.5, p = 0.01), but did not correlate with the C2-C7 Cobb angle (S = 0.20, p = 0.12) or C2-C7 SVA (S =  - 0.17, p = 0.46). (p < 0.05). ROC curve analysis showed that the areas under the curve (AUCs) of the T1 slope and LKA was 0.6696 and 0.7646, respectively. T1 slope, cutoff value: 17.2°; sensitivity: 0.5806; specificity: 0.7241; p < 0.05. LKA: cutoff value: - 14°; sensitivity: 1; specificity: 0.5333; p < 0.05.

conclusionsIn patients with Hirayama disease, the strength of posterior cervical extensors and cervical sagittal alignment are closely related. The local kyphosis angle can be used as a reference for the strength of posterior cervical extensors. These results indicate the weakness of PCEs, which may predispose the cervical spine of HD patients to a less stable situation. Therefore, patients with Hirayama disease should strengthen the exercise of the PCEs.

Indexed as

LordosisAdolescentCervical VertebraeFemaleHumansKyphosisMaleRetrospective StudiesSpinal Muscular Atrophies of ChildhoodTreatment OutcomeYoung AdultCervical spineCross-sectional areaHirayama diseaseLocal kyphotic deformityPosterior cervical extensors

Identifiers

PMID35033149
PMCPMC8760638
OpenAlexW4205988523

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.