ReviewCancer cell international2022
The Prognostic value of the Fibrinogen to pre-albumin ratio in malignant tumors of the digestive system: a systematic review and meta-analysis.
Review in Cancer cell international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prognostic value of fibrinogen to albumin ratio in malignant tumor patients: A meta-analysis.Frontiers in oncology · 2022Pooled it
- NPHR, FPR, and PLT as predictors of ulcerative colitis severity: a single-center retrospective study in China.Frontiers in medicine · 2026Article
- Preoperative Fibrinogen-to-Prealbumin Ratio and in-Hospital Postoperative Pneumonia After Minimally Invasive McKeown Esophagectomy for Esophageal Squamous Cell Carcinoma: A Retrospective Cohort Study with Infection Phenotype Profiling.Infection and drug resistance · 2026Article
- The potential value of fibrinogen-to-albumin ratio in assessing disease activity in rheumatoid arthritis.Frontiers in immunology · 2025Article
- Establishment and validation of a prediction model for gastric cancer with perineural invasion based on preoperative inflammatory markers.Translational cancer research · 2024Article
- Fibrinogen to pre-albumin ratio is an independent prognostic index for patients with pancreatic ductal adenocarcinoma after radical resection.World journal of surgical oncology · 2024Article
- Article
- C-reactive protein to albumin ratio predict responses to programmed cell death-1 inhibitors in hepatocellular carcinoma patients.World journal of gastrointestinal oncology · 2024Article
- Prediction of injury localization in preoperative patients with gastrointestinal perforation: a multiomics model analysis.BMC gastroenterology · 2024Article
- Prognostic Value of Fibrinogen to Prealbumin Ratio (FPR) in Resectable Gastric Cancer.Journal of inflammation research · 2024Article
- A nomogram based on inflammation and nutritional biomarkers for predicting the survival of breast cancer patients.Frontiers in endocrinology · 2024Article
- The prognostic role of coagulation markers in the progression and metastasis of laryngeal squamous cell carcinoma.BMC cancer · 2023Article
- The Prognostic Role of Circulating FPR Before Operation in Patients with BCLC A-C Hepatocellular Carcinoma: A Retrospective Cohort Study.Journal of hepatocellular carcinoma · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundIn recent years, the Fibrinogen to pre-albumin ratio (FPR) has been reported in many studies to be significantly associated with the prognosis of various cancers. This systematic review and meta-analysis aimed to investigate the prognostic value of FPR in malignant tumors of the digestive system based on available evidence.
methodsThe relevant articles published before July 1, 2021, were systematically retrieved from electronic databases to evaluate the effect of Fibrinogen to pre-albumin ratio (FPR) on the prognosis of patients with malignant digestive system tumors and calculate the hazard ratio (HR) and the corresponding 95% confidence interval (CI).
resultThirteen articles, all from China, including 15 cohort studies and a total of 5116 cases, were included in this study. A high FPR was associated with poor overall survival (HR = 1.88, 95%CI 1.53-2.32, P < 0.001), recurrence-free survival (HR = 2.29, 95%CI 1.91-2.76, P < 0.001), progression-free survival (HR = 1.96, 95%CI: 1.33-2.90, P = 0.001), complications (HR = 1.78, 95%CI: 1.06-3.00, P = 0.029), disease-free survival (HR = 1.46, 95%CI: 1.08-1.97, P = 0.013) was significantly associated with cancer-specific survival (HR = 1.44, 95%CI: 1.15-1.79, P = 0.001). Even though intergroup differences were present, FPR was strongly associated with overall and relapse-free survival, and sensitivity analysis suggested that our results were stable.
conclusionFPR can be used as a valuable indicator to predict the prognosis of patients with malignant digestive system tumors.
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