Evidence map›Paper›PMID 35033055›Full record

ArticleBMC pulmonary medicine2022

A new tool to screen patients with severe obstructive sleep apnea in the primary care setting: a prospective multicenter study.

Patricia Peñacoba, Maria Antònia Llauger, Ana María Fortuna, Xavier Flor, Gabriel Sampol, Anna Maria Pedro-Pijoan, Núria Grau, Carme Santiveri, Joan Juvanteny, José Ignacio Aoiz and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02591979 (PASHOS Project), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02591979 completednot on this map

PASHOS Project: Advanced Platform for Sleep Apnea Syndrome Assessment. A Multi-Centre Study to Validate a Sleep Apnea Screening Model in Primary Health Care

Typeobservational_patient_registrySponsorFundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauRan2015 to 2018Enrolled198ConditionsSleep Apnea Syndrome
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Chinese Guidelines for the Diagnosis and Surgical Treatment of Adult Obstructive Sleep Apnea (2024).World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
  2. Impact of Alzheimer's disease on sleep in adults with Down syndrome.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Patricia PeñacobaSleep Unit, Department of Respiratory Diseases, Hospital de La Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain. ppenacoba@santpau.cat.ORCID http://orcid.org/0000-0001-8943-7425
Maria Antònia LlaugerDepartment of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.
Ana María FortunaSleep Unit, Department of Respiratory Diseases, Hospital de La Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Xavier FlorDepartment of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.
Gabriel SampolDepartment of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.
Anna Maria Pedro-PijoanÀrea Bàsica de Salut Gaudí, Consorci Sanitari Integral, Barcelona, Spain.
Núria GrauCentro de Investigación Biomédica en Red Enfermedades Respiratorias (CIBERES), Instituto de Investigación Carlos III, Madrid, Spain.
Carme SantiveriService of Pneumology, Hospital Dos de Maig, Consorci Sanitari Integral, Barcelona, Spain.
Joan JuvantenyDepartment of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.
José Ignacio AoizCAP El Clot, Institut Català de La Salut, Barcelona, Spain.
Joan BayóCAP El Clot, Institut Català de La Salut, Barcelona, Spain.
Patricia LloberesSleep Unit, Service of Pneumology, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
Mercè MayosSleep Unit, Department of Respiratory Diseases, Hospital de La Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
PASHOS Working Group

Funding

fondo de investigaciones sanitarias PI 14/01985
6 · The paper itself

Abstract

backgroundThe coordination between different levels of care is essential for the management of obstructive sleep apnea (OSA). The objective of this multicenter project was to develop a screening model for OSA in the primary care setting.

methodsAnthropometric data, clinical history, and symptoms of OSA were recorded in randomly selected primary care patients, who also underwent a home sleep apnea test (HSAT). Respiratory polygraphy or polysomnography were performed at the sleep unit to establish definite indication for continuous positive airway pressure (CPAP). By means of cross-validation, a logistic regression model (CPAP yes/no) was designed, and with the clinical variables included in the model, a scoring system was established using the β coefficients (PASHOS Test). In a second stage, results of HSAT were added, and the final accuracy of the model was assessed.

results194 patients completed the study. The clinical test included the body mass index, neck circumference and observed apneas during sleep (AUC 0.824, 95% CI 0.763-0.886, P < 0.001). In a second stage, the oxygen desaturation index (ODI) of 3% (ODI3% ≥ 15%) from the HSAT was added (AUC 0.911, 95% CI 0.863-0.960, P < 0.001), with a sensitivity of 85.5% (95% CI 74.7-92.1) and specificity of 67.8% (95% CI 55.1-78.3).

conclusionsThe use of this model would prevent referral to the sleep unit for 55.1% of the patients. The two-stage PASHOS model is a useful and practical screening tool for OSA in primary care for detecting candidates for CPAP treatment. Clinical Trial Registration Registry: ClinicalTrials.gov; Name: PASHOS Project: Advanced Platform for Sleep Apnea Syndrome Assessment; URL: https://clinicaltrials.gov/ct2/show/NCT02591979 ; Identifier: NCT02591979. Date of registration: October 30, 2015.

Indexed as

Diagnostic Techniques and ProceduresHealth Status IndicatorsAdolescentAdultAgedContinuous Positive Airway PressureFemaleHumansMaleMiddle AgedPolysomnographyPrimary Health CareProspective StudiesReferral and ConsultationSleep Apnea, ObstructiveSpainContinuous positive airway pressure (CPAP)Home sleep apnea testObstructive sleep apneaPrimary healthcareScreening modelSleep unit

Identifiers

PMID35033055
PMCPMC8761286

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.