Evidence map›Paper›PMID 35033020›Full record

ReviewBMC infectious diseases2022

Secondary hypogonadism following hand, foot, and mouth disease in an adult: a case report and review of literature.

Zhaoying Chen, Chen Jiang, Xiaoyu Cheng, Lidan Ma, Ying Xin, Tian Liu, Ruixia Sun

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Hand, Foot, and Mouth Disease: A Narrative Review.Recent advances in inflammation & allergy drug discovery · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zhaoying ChenDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Chen JiangDepartment of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Xiaoyu ChengDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Lidan MaDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Ying XinDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Tian LiuDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Ruixia SunDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China. 18678991617@163.com.ORCID http://orcid.org/0000-0001-9788-2422
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious reports have described hypogonadism associated with virus infection such as hantavirus, human immunodeficiency virus (HIV) or severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). However, to our best knowledge there has been no case report of secondary hypogonadism following hand, foot, and mouth disease (HFMD). CASE PRESENTATION: A previously healthy 28-year-old man with no history of major physical and psychological trauma, presented with bilateral gynecomastia and erectile dysfunction 2 weeks after HFMD. Laboratory testament showed the level of gonadotropin hormones declined. Imaging examination demonstrated no major abnormal change in pituitary or reproductive system. The diagnosis of hypogonadism was established. Then the patient was ordered to maintain mental health outward of hospital without drug intervention. One month after presentation, his gonadotropin hormone level and sexual desire had recovered, while bilateral gynecomastia and erectile dysfunction symptoms disappeared.

conclusionsPhysicians should notice the possibility for hypogonadism in adult patients with a recent history of HFMD.

Indexed as

COVID-19Erectile DysfunctionHand, Foot and Mouth DiseaseHypogonadismAdultHumansMaleSARS-CoV-2Adult-onsetCase reportHand-foot-mouth diseaseHypogonadism

Identifiers

PMID35033020
PMCPMC8760742
OpenAlexW4206469790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.