Evidence map›Paper›PMID 35032871›Full record

ArticleThe Knee2022

Revision total knee arthroplasty outcomes in solid organ transplant Patients, a matched cohort study of aseptic and infected revisions.

Alexander Upfill-Brown, Shannon Y Wu, Christopher Hart, Peter P Hsiue, Clark J Chen, Danielle Ponzio, Christos Photopoulos, Alexandra I Stavrakis

Abstract read
In one paragraph

Article in The Knee, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander Upfill-BrownDepartment of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address: aupfillbrown@mednet.ucla.edu.
Shannon Y WuDepartment of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address: SYWu@mednet.ucla.edu.
Christopher HartDepartment of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address: Chart@mednet.ucla.edu.
Peter P HsiueDepartment of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address: phsiue@mednet.ucla.edu.
Clark J ChenDepartment of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address: cjc217@med.miami.edu.
Danielle PonzioRothman Institute at Thomas Jefferson University, Egg Harbor Township, NJ, USA. Electronic address: danielle.ponzio@rothmanortho.com.
Christos PhotopoulosCedars-Sinai Kerlan-Jobe Orthopaedic Institute, Los Angeles, CA, USA. Electronic address: christos.photopoulos@cskerlanjobe.org.
Alexandra I StavrakisDepartment of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address: astavrakis@mednet.ucla.edu.

Funding

Regenerative Musculoskeletal Medicine Training ProgramT32AR059033 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI John S Adams, Nicholas M. Bernthal · 2011 to 2026
$4.8M
NIAMS NIH HHS T32 AR059033
6 · The paper itself

Abstract

backgroundPrevious studies have demonstrated that solid organ transplant (SOT) patients undergoing primary total knee arthroplasty (TKA) are at an increased risk of postoperative complications. The purpose of this study is to utilize a large, national database to investigate revision TKA (rTKA) outcomes in SOT patients.

methodsThis was a retrospective review utilizing the Nationwide Readmissions Database (NRD) and ICD-9 codes to identify patients who underwent rTKA from 2010-2014 with a history of at least one SOT. Propensity-score-matching (PSM) was used to compare rTKA outcomes in SOT patients compared to matched patients without SOT.

resultsA total of 303,867 rTKAs, with 464 of those being performed in SOT patients, were included in the study. Of these, 71,903 and 182 were performed for PJI in non-SOT and SOT patients, respectively. rTKA was performed most frequently in kidney transplant patients (53.0%) followed by liver transplant patients (34.3%). For non-PJI patients, SOT patients had a higher 90-day readmission rate than matched non-SOT rTKA patients (23.2% vs 12.6%, p = 0.006). However, there were no differences in 90-day readmission rates for specific rTKA complications, subsequent revision rTKA, or mortality. Among patients undergoing rTKA for PJI, there was no difference in overall 90-day readmission rate, readmission for specific rTKA complications, subsequent revision rTKA, or mortality.

conclusionsWhile the increased medical comorbidities associated with SOT place patients at increased risk for complications following rTKA, it appears that SOT alone does not do so when patients are matched based on overall medical comorbidity.

Indexed as

Arthroplasty, Replacement, KneeOrgan TransplantationCohort StudiesHumansReoperationRetrospective StudiesProsthetic joint infectionRevision total knee arthroplastySolid organ transplantSurgical outcomes

Identifiers

PMID35032871
PMCPMC10463553

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.