Evidence map›Paper›PMID 35032627›Full record

ArticleOsteoarthritis and cartilage2022

Mechanisms of energy dissipation and relationship with tissue composition in human meniscus.

A Morejon, A M A Mantero, T M Best, A R Jackson, F Travascio

Open access · greenAbstract read
In one paragraph

Article in Osteoarthritis and cartilage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

A MorejonDepartment of Mechanical and Aerospace Engineering, University of Miami, Coral Gables, FL, USA.
A M A ManteroDepartment of Public Health Sciences, University of Miami, Coral Gables, FL, USA.
T M BestDepartment of Biomedical Engineering, University of Miami, Coral Gables, FL, USA; Department of Orthopaedic Surgery, University of Miami, Miami, FL, USA; UHealth Sports Medicine Institute, Coral Gables, FL, USA.
A R JacksonDepartment of Biomedical Engineering, University of Miami, Coral Gables, FL, USA. Electronic address: a.jackson2@miami.edu.
F TravascioDepartment of Mechanical and Aerospace Engineering, University of Miami, Coral Gables, FL, USA; Department of Orthopaedic Surgery, University of Miami, Miami, FL, USA; Max Biedermann Institute for Biomechanics at Mount Sinai Medical Center, Miami Beach, FL, USA. Electronic address: f.travascio@miami.edu.
University of Miami · US

Funding

Novel Computational Biomechanics Approach to Design of Bioengineered Tissue Construct for Meniscus Defect RepairR01AR073222 · NIAMS · UNIVERSITY OF MIAMI CORAL GABLES · PI JACKSON, ALICIA R, TRAVASCIO, FRANCESCO · 2018 to 2021
$1.3M
NIAMS NIH HHS R01 AR073222
6 · The paper itself

Abstract

objectiveThe human meniscus is essential in maintaining proper knee joint function. The meniscus absorbs shock, distributes loads, and stabilizes the knee joint to prevent the onset of osteoarthritis. The extent of its shock-absorbing role can be estimated by measuring the energy dissipated by the meniscus during cyclic mechanical loading.

methodsSamples were prepared from the central and horn regions of medial and lateral human menisci from 8 donors (both knees for total of 16 samples). Cyclic compression tests at several compression strains and frequencies yielded the energy dissipated per tissue volume. A GEE regression model was used to investigate the effects of compression, meniscal side and region, and water content on energy dissipation in order to account for repeated measures within samples.

resultsEnergy dissipation by the meniscus increased with compressive strain from ∼0.1 kJ/m

conclusionThe extent of energy dissipated by the meniscus is inversely related to loading frequency and meniscal water content.

Indexed as

Menisci, TibialMeniscusHumansKneeKnee JointWaterWaterCyclic compressionHysteresisMeniscal dampeningWater content

Identifiers

PMID35032627
PMCPMC8940718
OpenAlexW4205646225

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.