ReviewMolecular diversity2022
Recent developments in green approaches for sustainable synthesis of indole-derived scaffolds.
Review in Molecular diversity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 20 citations in OpenAlex.
- Recent Advances in the Synthesis of Spirooxindoles: A Comprehensive Review Organized by Ring Size, Heteroatom Incorporation, and Synthetic Approaches.Topics in current chemistry (Cham) · 2025Review
- Modular synthetic routes to biologically active indoles from lignin.Green chemistry : an international journal and green chemistry resource : GC · 2025Article
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Authors and funding
4 authors at 1 institution in 1 country.
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Abstract
An important issue to discover biological structures is the design of sustainable, safe, clean, cost-effective, excellent efficient synthetic reactions, and minimal energy consumption to provide structural diversity compounds with interesting biological properties. Among five-membered nitrogen-containing heterocyclic compounds, indole-containing scaffolds are heterocyclic structures found in abundance in natural products and various synthetic compounds, which have received remarkable attention in recent years due to their therapeutic and pharmaceutical properties and valuable role in the process of drug discovery. Indoles can be synthesized by various procedures although most of these procedures have their own restrictions and drawbacks such as performing the reaction in a toxic solvent, need of transition-metal catalysts, and amount of waste solvents. Due to the medicinal importance of indole and the need for green methods of drug synthesis, this review highlights the latest green synthetic methods leading to the formation of indole-containing compounds focusing on the past 4 years with typical examples. This review is divided into two sections: green solvents and green techniques that lead to the synthesis of indole-derived scaffolds.
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Registered trials
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