Evidence map›Paper›PMID 35031926›Full record

ReviewMolecular biology reports2022

Functions of lncRNA DUXAP8 in non-small cell lung cancer.

Cui Wu, Wu Song, Zhongnan Wang, Bingmei Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cui WuCollege of Integrated Traditional Chinese and Western Medicine, Changchun University of Chinese Medicine, No. 1035 Boshuo Road, Changchun, 130117, Jilin, China.
Wu SongCollege of Integrated Traditional Chinese and Western Medicine, Changchun University of Chinese Medicine, No. 1035 Boshuo Road, Changchun, 130117, Jilin, China. five841110@126.com.ORCID http://orcid.org/0000-0002-1314-8018
Zhongnan WangCollege of Integrated Traditional Chinese and Western Medicine, Changchun University of Chinese Medicine, No. 1035 Boshuo Road, Changchun, 130117, Jilin, China. zhongnanw@sina.com.
Bingmei WangCollege of Integrated Traditional Chinese and Western Medicine, Changchun University of Chinese Medicine, No. 1035 Boshuo Road, Changchun, 130117, Jilin, China. bingmeiwang1970@163.com.

Funding

Department of Science and Technology of Jilin Province 20180201086YYDepartment of Science and Technology of Jilin Province 20200404085YY
6 · The paper itself

Abstract

Non-small cell lung cancer (NSCLC) poses a serious threat to public health due to its significant morbidity and mortality rates. The processes of NSCLC formation and development are quite complex and involve numerous regulatory biomolecules. Long non-coding RNAs (lncRNAs) have attracted attention since they have been found to play critical roles in the tumorigenesis of various human malignancies. Recently, double homeobox A pseudogene 8 (DUXAP8) was identified as an oncogenic lncRNA that is overexpressed in different tumor types. In NSCLC, high expression of DUXAP8 is associated with poor prognosis in patients. The regulatory mechanism underlying the oncogenic effects of DUXAP8 can be divided into transcriptional level and post-transcriptional level. DUXAP8 promotes proliferation, epithelial-mesenchymal transition, and aerobic glycolysis in NSCLC cells. Moreover, DUXAP8 shows potential for the diagnosis and treatment of NSCLC. Herein, we review the molecular mechanisms underlying the DUXAP8-mediated phenotypes of NSCLC as well as its potential clinical applications.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsMicroRNAsRNA, Long NoncodingCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticGenes, HomeoboxHumansPseudogenesMicroRNAsRNA, Long NoncodingDUXAP8Long non-coding RNANon-small cell lung cancerOncogenePseudogene

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.