Evidence map›Paper›PMID 35031855›Full record

ArticlePediatric radiology2022

Agreement between serum estimates of glomerular filtration rate (GFR) and a reference standard of radioisotopic GFR in children with cancer.

Samjhana Thapaliya, Andrew J Sung, Susan E Sharp, Brian K Turpin, Bin Zhang, Edward J Nehus, Andrew T Trout

Abstract read
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In one paragraph

Article in Pediatric radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. [Current clinical application of glomerular filtration rate assessment methods in pediatric populations].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samjhana ThapaliyaDepartment of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., MLC 5031, Cincinnati, OH, 45229, USA.
Andrew J SungDepartment of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., MLC 5031, Cincinnati, OH, 45229, USA.
Susan E SharpDepartment of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., MLC 5031, Cincinnati, OH, 45229, USA.
Brian K TurpinCancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Bin ZhangDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Edward J NehusHoops Family Children's Hospital, Marshall University Joan C. Edwards School of Medicine, Huntington, WV, USA.
Andrew T TroutDepartment of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., MLC 5031, Cincinnati, OH, 45229, USA. andrew.trout@cchmc.org.ORCID 0000-0003-1431-4054

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate assessment of renal function is important in the care of children with cancer because renal function has implications for anti-tumor medication dosing and eligibility for clinical trials.

objectiveTo characterize agreement between serum estimates of glomerular filtration rate (GFR) and a reference standard of radioisotopic GFR in a large pediatric oncology cohort. MATERIALS AND

methodsWe conducted a retrospective cross-sectional study of children who had both radioisotopic GFR (

resultsWe included 272 pairs of data. Mean patient age was (mean ± standard deviation) 7.8±5.7 years. Mean radioisotopic GFR was 112±33 mL/min/1.73 m

conclusionAgreement between radioisotopic GFR and serum estimates of GFR is only fair and serum estimates of GFR have poor sensitivity for clinically relevant GFR <60 mL/min/1.73 m

Indexed as

NeoplasmsTechnetium Tc 99m PentetateAdolescentChildChild, PreschoolCross-Sectional StudiesGlomerular Filtration RateHumansReference StandardsRetrospective StudiesTechnetium Tc 99m PentetateChildrenGlomerular filtration rateKidneyKidney diseaseNuclear medicineOncologyScintigraphy

Identifiers

PMID35031855

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.