ArticleHorticulture research2022
The NAC-like transcription factor CsNAC7 positively regulates the caffeine biosynthesis-related gene yhNMT1 in Camellia sinensis.
Article in Horticulture research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 41 citations in OpenAlex.
- CsDRMH3 in tea plant (Camellia sinensis): functional study on mediating caffeine biosynthesis in relation to bud dormancy status.BMC plant biology · 2026Article
- Spatial transcriptome analysis of the tea tender shoot sheds light on transcriptional regulation of characteristic metabolites.Horticulture research · 2026Article
- JA Regulates Caffeine Biosynthesis in Tea Leaf for Resistance Against Fungal Infection and Antagonises With GA to Balance the Defence-Growth Trade-Off via CsDELLA-JAZ-MYC2-MYB184-TCS1 Module.Plant biotechnology journal · 2025Article
- Genome-wide identification and expression pattern analysis of NAC family in Taxus yunnanensis and the TyuNAC30 role in paclitaxel production.BMC genomics · 2025Article
- CsNAC17 enhances resistance toHorticulture research · 2025Article
- Evolution of the biochemistry underpinning purine alkaloid metabolism in plants.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Article
- mRNA-miRNA analyses reveal the involvement of CsbHLH1 and miR1446a in the regulation of caffeine biosynthesis inHorticulture research · 2024Article
- The transcription factor CsS40 negatively regulatesHorticulture research · 2023Article
- Identification of the NAC Transcription Factor Family during Early Seed Development inPlants (Basel, Switzerland) · 2023Article
- The NAC transcription factor family inFrontiers in plant science · 2023Article
- Identification of the NAC Transcription Factors and Their Function in ABA and Salinity Response inInternational journal of molecular sciences · 2022Article
- Article
- The Physiology of Postharvest Tea (Molecules (Basel, Switzerland) · 2022Article
- Metabolome and RNA-seq Analysis of Responses to Nitrogen Deprivation and Resupply in Tea Plant (Frontiers in plant science · 2022Article
- UPLC-MS/MS Profile Combined With RNA-Seq Reveals the Amino Acid Metabolism inFrontiers in nutrition · 2022Article
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Authors and funding
8 authors at 1 institution in 1 country.
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Abstract
Caffeine is an important functional substance and is abundant in tea plant, but little is known about how its biosynthesis is regulated by transcription factors. In this study, the NAC-like transcription factor-encoding gene CsNAC7, which is involved in caffeine synthesis, was isolated from a Yinghong 9 cDNA library using a yeast one-hybrid assay; this gene comprises 1371 bp nucleotides and is predicted to encode 456 amino acids. The expression of CsNAC7 at the transcriptional level in tea shoots shared a similar pattern with that of the caffeine synthase gene yhNMT1 in the spring and summer, and its expressed protein was localized in the nucleus. Assays of gene activity showed that CsNAC7 has self-activation activity in yeast, that the active region is at the N-terminus, and that the transient expression of CsNAC7 could significantly promote the expression of yhNMT1 in tobacco leaves. In addition, overexpression or silencing of CsNAC7 significantly increased or decreased the expression of yhNMT1 and the accumulation of caffeine in transgenic tea calli, respectively. Our data suggest that the isolated transcription factor CsNAC7 positively regulates the caffeine synthase gene yhNMT1 and promotes caffeine accumulation in tea plant.
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