Evidence map›Paper›PMID 35031687›Full record

ArticleNPJ digital medicine2022

An automated COVID-19 triage pipeline using artificial intelligence based on chest radiographs and clinical data.

Chris K Kim, Ji Whae Choi, Zhicheng Jiao, Dongcui Wang, Jing Wu, Thomas Y Yi, Kasey C Halsey, Feyisope Eweje, Thi My Linh Tran, Chang Liu and 23 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
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  6. N-of-1 medicine.Singapore medical journal · 2024
    Article
  7. Article
  8. Article
  9. A snapshot of artificial intelligence research 2019-2021: is it replacing or assisting physicians?Journal of the American Medical Informatics Association : JAMIA · 2023
    Review
  10. Article
  11. Article
  12. Radiomics analysis in medical imaging research.Journal of medical radiation sciences · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Chris K Kim *Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, 02903, USA.ORCID http://orcid.org/0000-0002-6146-3581
Ji Whae Choi *Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, 02903, USA.
Zhicheng Jiao *Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, 02903, USA.
Dongcui WangDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Jing WuDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Thomas Y YiDepartment of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, 02903, USA.
Kasey C HalseyDepartment of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, 02903, USA.
Feyisope EwejePerelman School of Medicine at University of Pennsylvania, Philadelphia, PA, 19104, USA.ORCID http://orcid.org/0000-0003-1417-7096
Thi My Linh TranDepartment of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, 02903, USA.
Chang LiuDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Robin WangPerelman School of Medicine at University of Pennsylvania, Philadelphia, PA, 19104, USA.
John SolleeDepartment of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, 02903, USA.
Celina HsiehDepartment of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, 02903, USA.
Ken ChangAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, 02129, USA.
Fang-Xue YangDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Ritambhara SinghDepartment of Computer Science, Brown University, Providence, RI, 02912, USA.
Jie-Lin OuDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Raymond Y HuangDepartment of Radiology, Brigham and Women's Hospital, Boston, MA, 02115, USA.
Cai FengDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Michael D FeldmanPerelman School of Medicine at University of Pennsylvania, Philadelphia, PA, 19104, USA.
Tao LiuDepartment of Biostatistics, Brown University, Providence, RI, 02912, USA.
Ji Sheng GongDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Shaolei LuDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Carsten EickhoffCenter for Biomedical Informatics, Brown University, Providence, RI, 02912, USA.ORCID http://orcid.org/0000-0001-9895-4061
Xue FengCarina Medical, Lexington, KY, 40513, USA.
Ihab KamelDepartment of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, MD, 21205, USA.
Ronnie SebroPerelman School of Medicine at University of Pennsylvania, Philadelphia, PA, 19104, USA.
Michael K AtalayDepartment of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, 02903, USA.
Terrance HealeyDepartment of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, 02903, USA.
Yong FanPerelman School of Medicine at University of Pennsylvania, Philadelphia, PA, 19104, USA.ORCID http://orcid.org/0000-0001-9869-4685
Wei-Hua LiaoDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China. owenliao@csu.edu.cn.
Jianxin WangSchool of Computer Science and Engineering, Central South University, Changsha, China. jxwang@mail.csu.edu.cn.ORCID http://orcid.org/0000-0003-1516-0480
Harrison X BaiDepartment of Diagnostic Imaging, Rhode Island Hospital, Providence, RI, 02903, USA. harrison_bai@brown.edu.ORCID http://orcid.org/0000-0002-7460-8866

Funding

Automatic Volumetric Treatment Response Assessment and Determination of Regional Genetic Characteristics in GlioblastomaF30CA239407 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI CHANG, KEN · 2019 to 2020
$101k
NCI NIH HHS F30 CA239407U.S. Department of Health & Human Services | NIH | Center for Information Technology (Center for Information Technology, National Institutes of Health) F30CA239407,
6 · The paper itself

Abstract

While COVID-19 diagnosis and prognosis artificial intelligence models exist, very few can be implemented for practical use given their high risk of bias. We aimed to develop a diagnosis model that addresses notable shortcomings of prior studies, integrating it into a fully automated triage pipeline that examines chest radiographs for the presence, severity, and progression of COVID-19 pneumonia. Scans were collected using the DICOM Image Analysis and Archive, a system that communicates with a hospital's image repository. The authors collected over 6,500 non-public chest X-rays comprising diverse COVID-19 severities, along with radiology reports and RT-PCR data. The authors provisioned one internally held-out and two external test sets to assess model generalizability and compare performance to traditional radiologist interpretation. The pipeline was evaluated on a prospective cohort of 80 radiographs, reporting a 95% diagnostic accuracy. The study mitigates bias in AI model development and demonstrates the value of an end-to-end COVID-19 triage platform.

Identifiers

PMID35031687
PMCPMC8760275

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.