ArticleNature communications2022
Model-based evaluation of alternative reactive class closure strategies against COVID-19.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 47 citations in OpenAlex.
- A systematic comparison of methodologies for the estimation of the serial interval.Infectious Disease Modelling · 2026Article
- The impact of school-based mitigation measures on the transmission of respiratory pathogens: the case of SARS-CoV-2.International journal of epidemiology · 2026Article
- Event-based spatiotemporal networks for modelling emergent phenomena in complex systems.Nature communications · 2026Article
- VIBES: A multiscale modeling approach integrating within-host and between-hosts dynamics in epidemics.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Risk mapping novel respiratory pathogens with large-scale dynamic contact networks.Communications medicine · 2026Article
- Surveillance of infectious diseases spreading on time-varying multiplex networks.Infectious Disease Modelling · 2026Article
- Assessing the effectiveness of test-trace-isolate interventions using a multi-layered temporal network.Infectious Disease Modelling · 2025Article
- Epidemic Dynamics and Intervention Measures in Campus Settings Based on Multilayer Temporal Networks.Entropy (Basel, Switzerland) · 2025Article
- MetaCity: Data-driven sustainable development of complex cities.Innovation (Cambridge (Mass.)) · 2025Review
- A modeling study to define guidelines for antigen screening in schools and workplaces to mitigate COVID-19 outbreaks.Communications medicine · 2025Article
- Decisions and Influential Factors Regarding Class-Specific School Closures Against Seasonal Influenza Outbreak.Cureus · 2024Article
- Article
- Evaluating the impact of test-trace-isolate for COVID-19 management and alternative strategies.PLoS computational biology · 2023Article
- Adaptive group testing strategy for infectious diseases using social contact graph partitions.Scientific reports · 2023Article
- Impacting factors and sources of perceived stress by home-quarantined residents in Shanghai during COVID-19 epidemic.BMC public health · 2023Article
- A high-frequency mobility big-data reveals how COVID-19 spread across professions, locations and age groups.PLoS computational biology · 2023Article
- COVID-19 Test Allocation Strategy to Mitigate SARS-CoV-2 Infections across School Districts.Emerging infectious diseases · 2023Article
- Minimising school disruption under high incidence conditions due to the Omicron variant in France, Switzerland, Italy, in January 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023Article
- Novel estimates reveal subnational heterogeneities in disease-relevant contact patterns in the United States.PLoS computational biology · 2022Article
- A COVID-19 model incorporating variants, vaccination, waning immunity, and population behavior.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
17 authors at 8 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are contrasting results concerning the effect of reactive school closure on SARS-CoV-2 transmission. To shed light on this controversy, we developed a data-driven computational model of SARS-CoV-2 transmission. We found that by reactively closing classes based on syndromic surveillance, SARS-CoV-2 infections are reduced by no more than 17.3% (95%CI: 8.0-26.8%), due to the low probability of timely identification of infections in the young population. We thus investigated an alternative triggering mechanism based on repeated screening of students using antigen tests. Depending on the contribution of schools to transmission, this strategy can greatly reduce COVID-19 burden even when school contribution to transmission and immunity in the population is low. Moving forward, the adoption of antigen-based screenings in schools could be instrumental to limit COVID-19 burden while vaccines continue to be rolled out.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.