Evidence map›Paper›PMID 35031564›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Regional synapse gain and loss accompany memory formation in larval zebrafish.

William P Dempsey, Zhuowei Du, Anna Nadtochiy, Colton D Smith, Karl Czajkowski, Andrey Andreev, Drew N Robson, Jennifer M Li, Serina Applebaum, Thai V Truong and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Negative-Valence Neurons in the Larval Zebrafish Pallium.bioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Neural Basis of Number Sense in Larval Zebrafish.bioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Synaptic input and CaNature neuroscience · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Quantitative Fluorescence Analysis Reveals Dendrite-Specific Thalamocortical Plasticity in L5 Pyramidal Neurons during Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  12. Article
  13. Article
  14. Regional synapse gain and loss accompany memory formation in larval zebrafish.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

William P DempseyDepartment of Biological Sciences, Division of Molecular and Computational Biology, University of Southern California, Los Angeles, CA 90089.
Zhuowei DuDepartment of Biological Sciences, Division of Molecular and Computational Biology, University of Southern California, Los Angeles, CA 90089.ORCID 0000-0001-8577-2656
Anna NadtochiyTranslational Imaging Center, University of Southern California, Los Angeles, CA 90089.ORCID 0000-0002-5520-2289
Colton D SmithDepartment of Biological Sciences, Division of Molecular and Computational Biology, University of Southern California, Los Angeles, CA 90089.
Karl CzajkowskiInformation Sciences Institute, University of Southern California, Los Angeles, CA 90292.
Andrey AndreevTranslational Imaging Center, University of Southern California, Los Angeles, CA 90089.ORCID 0000-0002-7833-1390
Drew N RobsonSystems Neuroscience & Neuroengineering, Max Planck Institute for Biological Cybernetics, 72076 Tübingen, Germany.
Jennifer M LiSystems Neuroscience & Neuroengineering, Max Planck Institute for Biological Cybernetics, 72076 Tübingen, Germany.
Serina ApplebaumDepartment of Biological Sciences, Division of Molecular and Computational Biology, University of Southern California, Los Angeles, CA 90089.ORCID 0000-0001-9062-6178
Thai V TruongTranslational Imaging Center, University of Southern California, Los Angeles, CA 90089.
Carl KesselmanInformation Sciences Institute, University of Southern California, Los Angeles, CA 90292.
Scott E FraserDepartment of Biological Sciences, Division of Molecular and Computational Biology, University of Southern California, Los Angeles, CA 90089.
Don B ArnoldDepartment of Biological Sciences, Division of Molecular and Computational Biology, University of Southern California, Los Angeles, CA 90089; darnold@usc.edu.ORCID 0000-0001-7378-1440
University of Southern California · USMax Planck Institute for Biological Cybernetics · DE

Funding

Dynamic mapping of the complete synaptome using recombinant probesR01MH107238 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ARNOLD, DONALD B, FRASER, SCOTT E · 2014 to 2018
$9.7M
Circuits underlying threat and safetyUF1NS122082 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ARNOLD, DONALD B, FRASER, SCOTT E · 2021 to 2021
$4.7M
NIMH NIH HHS R01 MH107238NINDS NIH HHS UF1 NS122082
6 · The paper itself

Abstract

Defining the structural and functional changes in the nervous system underlying learning and memory represents a major challenge for modern neuroscience. Although changes in neuronal activity following memory formation have been studied [B. F. Grewe et al.,

Indexed as

AmygdalaAnimalsConditioning, ClassicalLarvaLearningMemoryNeuronsSynapsesZebrafishclassical conditioninglearning and memorypalliumsynapsezebrafish

Identifiers

PMID35031564
PMCPMC8784156
OpenAlexW4206594452

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.