Evidence map›Paper›PMID 35031023›Full record

ArticleBMC endocrine disorders2022

Prevalence of asymptomatic hyperuricemia and its association with prediabetes, dyslipidemia and subclinical inflammation markers among young healthy adults in Qatar.

Yasemin Al Shanableh, Yehia Y Hussein, Abdul Haseeb Saidwali, Maryam Al-Mohannadi, Budoor Aljalham, Hamnah Nurulhoque, Fahad Robelah, Areej Al-Mansoori, Susu M Zughaier

Open access · goldAbstract read
In one paragraph

Article in BMC endocrine disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

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  14. Plantaginis Semen Ameliorates Hyperuricemia Induced by Potassium Oxonate.International journal of molecular sciences · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yasemin Al Shanableh *College of Medicine, QU Health, Qatar University, PO Box 2713, Doha, Qatar.
Yehia Y Hussein *College of Medicine, QU Health, Qatar University, PO Box 2713, Doha, Qatar.
Abdul Haseeb SaidwaliCollege of Medicine, QU Health, Qatar University, PO Box 2713, Doha, Qatar.
Maryam Al-MohannadiCollege of Medicine, QU Health, Qatar University, PO Box 2713, Doha, Qatar.
Budoor AljalhamCollege of Medicine, QU Health, Qatar University, PO Box 2713, Doha, Qatar.
Hamnah NurulhoqueCollege of Medicine, QU Health, Qatar University, PO Box 2713, Doha, Qatar.
Fahad RobelahCollege of Medicine, QU Health, Qatar University, PO Box 2713, Doha, Qatar.
Areej Al-MansooriCollege of Medicine, QU Health, Qatar University, PO Box 2713, Doha, Qatar.
Susu M ZughaierCollege of Medicine, QU Health, Qatar University, PO Box 2713, Doha, Qatar. szughaier@qu.edu.qa.
Qatar University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study is to investigate the prevalence of asymptomatic hyperuricemia in Qatar and to examine its association with changes in markers of dyslipidemia, prediabetes and subclinical inflammation.

methodsA cross-sectional study of young adult participants aged 18 - 40 years old devoid of comorbidities collected between 2012 and 2017. Exposure was defined as uric acid level, and outcomes were defined as levels of different blood markers. De-identified data were collected from Qatar Biobank. T-tests, correlation tests and multiple linear regression were all used to investigate the effects of hyperuricemia on blood markers. Statistical analyses were conducted using STATA 16.

resultsThe prevalence of asymptomatic hyperuricemia is 21.2% among young adults in Qatar. Differences between hyperuricemic and normouricemic groups were observed using multiple linear regression analysis and found to be statistically and clinically significant after adjusting for age, gender, BMI, smoking and exercise. Significant associations were found between uric acid level and HDL-c p = 0.019 (correlation coefficient -0.07 (95% CI [-0.14, -0.01]); c-peptide p = 0.018 (correlation coefficient 0.38 (95% CI [0.06, 0.69]) and monocyte to HDL ratio (MHR) p = 0.026 (correlation coefficient 0.47 (95% CI [0.06, 0.89]).

conclusionsAsymptomatic hyperuricemia is prevalent among young adults and associated with markers of prediabetes, dyslipidemia, and subclinical inflammation.

Indexed as

AdolescentAdultBiomarkersCross-Sectional StudiesDyslipidemiasFemaleHumansHyperuricemiaInflammationMalePrediabetic StatePrevalenceQatarUric AcidBiomarkersUric AcidAsymptomatic hyperuricemiaPrediabetesQatar BiobankSubclinical inflammationUric acid

Identifiers

PMID35031023
PMCPMC8760639
OpenAlexW4225789493

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.