Observational studyPloS one2022
COVID-19-associated acute kidney injury patients treated with renal replacement therapy in the intensive care unit: A multicenter study in São Paulo, Brazil.
Observational study in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- High-Flow Nasal Cannula Application After Extubation in Acute Respiratory Failure Patients.Journal of clinical medicine · 2025Article
- LBP and iFABP mismatch in the evaluation of intestinal barrier dysfunction due to SARS-CoV-2 infection.Clinics (Sao Paulo, Brazil) · 2025Observational
- Clinical management and outcomes in severe COVID-19: acute respiratory distress syndrome across two waves.Revista da Escola de Enfermagem da U S P · 2025Article
- Article
- Long-term outcome of COVID-19 patients with acute kidney injury requiring kidney replacement therapy.Journal of anesthesia, analgesia and critical care · 2024Article
- Observational
- Kidney replacement therapy in COVID-19-Related acute kidney injury: The impact of timing on mortality.PloS one · 2024Article
- Article
- Multistate Modeling of Clinical Trajectories and Outcomes in the ICU: A Proof-of-Concept Evaluation of Acute Kidney Injury Among Critically Ill Patients With COVID-19.Critical care explorations · 2022Article
- Medical students' and health professionals' knowledge regarding acute kidney injury: a cross-sectional study in the city of São Paulo, Brazil.Renal failure · 2022Article
- Group-based trajectory modeling to identify health beliefs of COVID-19 vaccination and its predictors: A cohort study in China.Human vaccines & immunotherapeutics · 2022Article
- Acute kidney injury in critically ill COVID-19 infected patients requiring dialysis: experience from India and Pakistan.BMC nephrology · 2022Article
- Acute Kidney Injury in COVID-19 Patients: Pathogenesis, Clinical Characteristics, Therapy, and Mortality.Diseases (Basel, Switzerland) · 2022Review
- Case fatality rate among COVID-19 patients treated with acute kidney replacement therapy.Jornal brasileiro de nefrologiaArticle
Corrections and comments
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Authors and funding
29 authors at 11 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMulticenter studies involving patients with acute kidney injury (AKI) associated with the disease caused by the new coronavirus (COVID-19) and treated with renal replacement therapy (RRT) in developing countries are scarce. The objectives of this study were to evaluate the demographic profile, clinical picture, risk factors for mortality, and outcomes of critically ill patients with AKI requiring dialysis (AKI-RRT) and with COVID-19 in the megalopolis of São Paulo, Brazil.
methodsThis multicenter, retrospective, observational study was conducted in the intensive care units of 13 public and private hospitals in the metropolitan region of the municipality of São Paulo. Patients hospitalized in an intensive care unit, aged ≥ 18 years, and treated with RRT due to COVID-19-associated AKI were included.
resultsThe study group consisted of 375 patients (age 64.1 years, 68.8% male). Most (62.1%) had two or more comorbidities: 68.8%, arterial hypertension; 45.3%, diabetes; 36.3%, anemia; 30.9%, obesity; 18.7%, chronic kidney disease; 15.7%, coronary artery disease; 10.4%, heart failure; and 8.5%, chronic obstructive pulmonary disease. Death occurred in 72.5% of the study population (272 patients). Among the 103 survivors, 22.3% (23 patients) were discharged on RRT. In a multiple regression analysis, the independent factors associated with death were the number of organ dysfunctions at admission and RRT efficiency.
conclusionAKI-RRT associated with COVID-19 occurred in patients with an elevated burden of comorbidities and was associated with high mortality (72.5%). The number of organ dysfunctions during hospitalization and RRT efficiency were independent factors associated with mortality. A meaningful portion of survivors was discharged while dependent on RRT (22.3%).
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