ArticleMedicine2022
Relationship between marital status and survival in patients with lung adenocarcinoma: A SEER-based study.
Article in Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Marital status and survival in cancer patients: A systematic review and meta-analysis.Cancer medicine · 2023Pooled it
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- A web-based prediction model for brain metastasis in non-small cell lung cancer patients.Discover oncology · 2025Article
- Delays in phases of care from identification to treatment of suspicious lung nodules.JTCVS open · 2025Article
- Clinicopathologic characteristics and prognosis of basaloid squamous cell carcinoma of the rectum in comparison with adenocarcinoma: a retrospective cohort study.Frontiers in oncology · 2025Article
- Marital status shows no protective effect on perioperative outcomes after robotic-assisted pulmonary lobectomy.Surgery in practice and science · 2024Article
- Correlation of CT features of lung adenocarcinoma with sex and age.Scientific reports · 2024Article
- Correlation between marital status and the prognosis of older patients with cerebrovascular disease in intensive care units: A retrospective cohort study.Health science reports · 2024Article
- Development and validation of a nomogram integrating marital status for 5-year overall survival of chondrosarcoma: a population-based study.Discover oncology · 2024Article
- Article
- Article
- The influence of marital status at diagnosis on survival of adult patients with mantle cell lymphoma.Journal of cancer research and clinical oncology · 2024Article
- Establishment and validation of nomograms for predicting survival of lung invasive adenocarcinoma based on the level of pathological differentiation: a SEER cohort-based analysis.Translational cancer research · 2023Article
- Development and Validation of Prognostic Nomograms for Lung Squamous Cell Carcinoma With Brain Metastasis in Patients Aged 45 Years or Older: A Population-Based Study.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
abstractNumerous studies have focused on whether the marital status has an impact on the prognosis in patients with non-small cell lung cancer, but none have focused on lung adenocarcinoma.We selected 61,928 eligible cases with lung adenocarcinoma from the Surveillance, Epidemiology, and End Results database from 2004 to 2016 and analyzed the impact of marital status on cancer-specific survival (CSS) using Kaplan-Meier and Cox regression analyses.We confirmed that sex, age, race, cancer TNM stage and grade, therapeutic schedule, household income, and marital status were independent prognostic factors for lung adenocarcinoma CSS. Multivariate Cox regression showed that widowed patients had worse CSS (hazard ratio 1.26, 95% confidence interval 1.20-1.31, P < .001) compared with married patients. Subgroup analysis showed consistent results regardless of sex, age, cancer grade, and TNM stage. However, the trend was not significant for patients with grade IV cancer.These results suggest that marital status is first identified as an independent prognostic factor for CSS in patients with lung adenocarcinoma, with a clear association between widowhood and a high risk of cancer-specific mortality. Psychological and social support are thus important for patients with lung adenocarcinoma, especially unmarried patients.
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