ArticleMedicine2022
Modified internal limiting membrane flap technique for large chronic macular hole: Two case reports.
Article in Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Assessment of internal limiting membrane flap and autologous whole blood techniques in complicated macular hole surgery.BMC ophthalmology · 2026Article
- Early-warning predictive model of retinal detachment in high myopia: a comprehensive construction and validation study.BMC ophthalmology · 2026Article
- Combined Surgically Induced Macular Detachment and Autologous Internal Limiting Membrane Transplantation for Refractory Full Thickness Macular Hole.Journal of clinical medicine · 2025Article
- Effect of internal limiting membrane surgical techniques on the idiopathic and refractory management of macular holes: a systematic review and meta-analysis.International journal of retina and vitreous · 2024Review
- Negative effects of enlarging internal limiting membrane peeling for idiopathic macular hole surgery.International journal of ophthalmology · 2022Article
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
rationaleInternal limiting membrane (ILM) peeling and gas tamponade are the standardized treatments for macular holes (MHs). However, the close rate is low, and postoperative vision is unsatisfactory in large, chronic MHs. Currently, various modifications of the ILM flap techniques are being gradually applied for large MHs in the hope of obtaining better postoperative effects. This study described 2 successful cases achieved by "Sandwich-type" modified ILM flap covering technique in patients with large, chronic MHs. PATIENT CONCERNS: A 62-year-old woman presented with decreased vision and visual distortion of the left eye for 18 months. Optical coherence tomography (OCT) showed the absence of full-thickness neuroepithelial tissue in the central fovea, with a minimum MH diameter of 742 μm and a base diameter of 1630 μm. A 57-year-old man experienced decreased visual acuity for 8 months. OCT showed the absence of full-thickness neuroepithelial tissue in the central fovea, with a minimum MH diameter of 713 μm and a basal diameter of 939 μm. DIAGNOSES: Two patients were diagnosed with large, chronic MH based on the OCT results and duration of the hole.
interventionsThe 2 patients were treated with the "sandwich-type" modified ILM flap covering technique. OUTCOMES: Large, chronic MH closure was observed using SD-OCT, and the BCVA improved. The patients were very satisfied with the postoperative results. LESSONS: "Sandwich-type" modified ILM flap covering technique may be a safe, effective way for large, chronic MH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.