Evidence map›Paper›PMID 35029844›Full record

ArticleAngewandte Chemie (International ed. in English)2022

Electrochemical Fluorination of Vinyl Boronates through Donor-Stabilized Vinyl Carbocation Intermediates.

Benjamin Wigman, Woojin Lee, Wenjing Wei, Kendall N Houk, Hosea M Nelson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Benjamin WigmanDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Woojin LeeDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Wenjing WeiDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Kendall N HoukDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Hosea M NelsonDepartment of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID http://orcid.org/0000-0002-4666-2793

Funding

Kinetically-Persistent Carbocationsin C-H Insertion Reactions and Biomimetic Cyclization CascadesR35GM128936 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NELSON, HOSEA MARTIN · 2018 to 2022
$1.9M
Alfred P. Sloan FoundationNational Institute of Health National Institute of General Medical Sciences R35GM12893National Science Foundation CHE-176432 , DGE165060NIGMS NIH HHS R35 GM128936
6 · The paper itself

Abstract

The electrochemical generation of vinyl carbocations from alkenyl boronic esters and boronates is reported. Using easy-to-handle nucleophilic fluoride reagents, these intermediates are trapped to form fully substituted vinyl fluorides. Mechanistic studies support the formation of dicoordinated carbocations through sequential single-electron oxidation events. Notably, this electrochemical fluorination features fast reaction times and Lewis acid-free conditions. This transformation provides a complementary method to access vinyl fluorides with simple fluoride salts such as TBAF.

Indexed as

Alkenyl BoronatesElectrochemistryFluorinationVinyl CarbocationsVinyl Fluorides

Identifiers

PMID35029844
PMCPMC8901537

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.