Evidence map›Paper›PMID 35029675›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2022

Association Between Mediterranean Diet and Functional Status in Older Adults: A Longitudinal Study Based on the Washington Heights-Inwood Columbia Aging Project.

Jing Guo, Nicole Schupf, Emily Cruz, Yaakov Stern, Richard P Mayeux, Yian Gu

Open access · greenAbstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
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  3. Increases in adherence to a simplified Mediterranean diet predicts improved next day cognitive functioning.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jing GuoThe Taub Institute for Research in Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.
Nicole SchupfThe Taub Institute for Research in Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.
Emily CruzThe Taub Institute for Research in Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.
Yaakov SternThe Taub Institute for Research in Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.
Richard P MayeuxThe Taub Institute for Research in Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.
Yian GuThe Taub Institute for Research in Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.
Columbia University · US

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
VASCULAR FACTORS AND MILD COGNITIVE IMPAIRMENT AND ALZHEIMER'S DISEASEP01AG007232 · NIA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI SCHUPF, NICOLE · 1989 to 2008
$21.7M
Epidemiological and Genetic Investigations of Blood-Based Biomarkers for Alzheimer's Disease in the Multiethnic, Washington Heights, Inwood, Columbia Aging Project (WHICAP)R01AG072474 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRICKMAN, ADAM M, MANLY, JENNIFER JAIE · 2021 to 2025
$13.3M
Epidemiological Integration of Genetic Variants and Metabolomics Profiles in Washington Heights Columbia Aging ProjectRF1AG066107 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P, MILLER, GARY W · 2020 to 2022
$11.4M
Epidemiology of Biomarkers of Risk and Progression in LOADR01AG037212 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P, SCHUPF, NICOLE · 2010 to 2015
$10.1M
Genetic Epidemiology of Cerebrovascular Factors in Alzheimer's DiseaseRF1AG054023 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P · 2016 to 2018
$8.9M
The role of inflammation in the association between diet and Alzheimer's diseaseR01AG059013 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GU, YIAN · 2019 to 2023
$3.7M
Diet and Cognition within a Reserve frameworkR01AG061008 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GU, YIAN · 2020 to 2024
$3.3M
Diet in relation to brain and cognitive health in a middle-aged multiethnic population: nutritional implications for aging and Alzheimer's disease.R56AG060156 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GU, YIAN, SCARMEAS, NIKOLAOS A · 2019 to 2019
$767k
NCATS NIH HHS UL1 TR001873NIA NIH HHS P01 AG007232NIA NIH HHS R01 AG037212NIA NIH HHS R01 AG059013NIA NIH HHS R01 AG061008NIA NIH HHS R01 AG072474NIA NIH HHS R56 AG060156NIA NIH HHS RF1 AG054023NIA NIH HHS RF1 AG066107
6 · The paper itself

Abstract

backgroundCurrent evidence on the association between Mediterranean diet (MeDi) intake and activities of daily living (ADL) is limited and inconsistent in older adults.

methodsThis study included 1 696 participants aged ≥65 years in the Washington Heights-Inwood Community Aging Project study. The MeDi score was calculated based on data collected from the Willett's semiquantitative food frequency questionnaire. The multivariable-adjusted Cox regression model was applied to examine the association of MeDi score with risks of disability in basic (BADL) and instrumental ADL (IADL), as well as the overall ADL (B-IADL).

resultsEight hundred and thirty-two participants with incident ADL disability were identified over a median follow-up of 5.39 years. The continuous MeDi score was significantly associated with decreased risk of disability in B-IADL (hazard ratio = 0.95, 95% confidence interval = 0.91-0.99, p = .018) in a model adjusted for age, sex, race/ethnicity, educational level, and dietary calories intake but was no longer significant after additionally adjusted for multiple comorbidities and physical activities (0.97 [0.93, 1.01], p = .121). The continuous MeDi score was significantly associated with decreased risk of disability in B-IADL (0.92 [0.85, 1.00], p = .043) and BADL (0.90 [0.82, 0.99], p = .030) in non-Hispanic Whites, but not in non-Hispanic Blacks and Hispanics (p > .05 for all).

conclusionsHigher MeDi score was associated with decreased risk of ADL disability, particularly in non-Hispanic Whites.

Indexed as

Diet, MediterraneanPersons with DisabilitiesActivities of Daily LivingAgedAgingFunctional StatusHumansLongitudinal StudiesWashingtonADLDisabilityEpidemiologyMediterranean diet

Identifiers

PMID35029675
PMCPMC9434425
OpenAlexW4206257185

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.