Evidence map›Paper›PMID 35029661›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2023

Free-Living Gait Cadence Measured by Wearable Accelerometer: A Promising Alternative to Traditional Measures of Mobility for Assessing Fall Risk.

Jacek K Urbanek, David L Roth, Marta Karas, Amal A Wanigatunga, Christine M Mitchell, Stephen P Juraschek, Yurun Cai, Lawrence J Appel, Jennifer A Schrack

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02166333 (Vitamin D Supplements to Prevent Falls in Older Adults), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02166333 naterminatednot on this map

Vitamin D Supplements to Prevent Falls in Older Adults: A Dose-Response Trial

TypeinterventionalSponsorJohns Hopkins UniversityRan2015 to 2019Enrolled688ConditionsVitamin D Deficiency, FallsArms200 IU/d cholecalciferol, 1000 IU/d cholecalciferol, 2000 IU/d cholecalciferol, 4000 IU/d cholecalciferol
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  3. Real-world walking and activity patterns in community-dwelling older adults: a cross-sectional analysis of baseline data from the SMART-AGE trial.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
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  18. Novel Technology-driven Approaches to Enhance Mobility and Reduce Falls in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jacek K UrbanekDivision of Geriatric Medicine and Gerontology, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0002-1890-8899
David L RothDivision of Geriatric Medicine and Gerontology, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0003-2105-0536
Marta KarasDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Amal A WanigatungaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-5763-5184
Christine M MitchellDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Stephen P JuraschekHarvard Medical School/Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.ORCID 0000-0003-4168-2696
Yurun CaiDepartment of Health and Community Systems, University of Pittsburgh School of Nursing, Pittsburgh, PA.ORCID 0000-0001-8264-8158
Lawrence J AppelWelch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland, USA.
Jennifer A SchrackCenter on Aging and Health, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0001-9244-9267
Johns Hopkins University · USBeth Israel Deaconess Medical Center · USHarvard University · USUniversity of Pittsburgh · US

Funding

QAQC Johns Hopkins Institute for Clinical and Translational ResearchUL1TR003098 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2019 to 2023
$57.7M
Research Education ComponentP30AG066507 · NIA · JOHNS HOPKINS UNIVERSITY · PI Arnold Bakker · 2020 to 2026
$29.3M
Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
Vitamin D Supplements to Prevent Falls in Older Adults: A Dose-Response TrialU01AG047837 · NIA · JOHNS HOPKINS UNIVERSITY · PI APPEL, LAWRENCE JOHN · 2014 to 2019
$9.5M
RENAL DISEASE EPIDEMIOLOGY TRAINING GRANTT32DK007732 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI CREWS, DEIDRA CANDICE · 1995 to 2024
$7.7M
Vitamin D, Subclinical Cardiovascular Disease, and Orthostatic Hypotension in Older AdultsK23HL135273 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI JURASCHEK, STEPHEN P · 2017 to 2021
$1.1M
Energy Expenditure, Activity, and Aging With HIV:Effects on Functional LongevityK01AG048765 · NIA · JOHNS HOPKINS UNIVERSITY · PI SCHRACK, JENNIFER ANN · 2014 to 2016
$388k
NCATS NIH HHS UL1 TR003098NHLBI NIH HHS K23 HL135273NIA NIH HHS K01 AG048765NIA NIH HHS P30 AG066507NIA NIH HHS U01 AG047837NIDDK NIH HHS P30 DK072488NIDDK NIH HHS T32 DK007732NIH HHS U01AG047837
6 · The paper itself

Abstract

backgroundWearable devices have become widespread in research applications, yet evidence on whether they are superior to structured clinic-based assessments is sparse. In this manuscript, we compare traditional, laboratory-based metrics of mobility with a novel accelerometry-based measure of free-living gait cadence for predicting fall rates.

methodsUsing negative binomial regression, we compared traditional in-clinic measures of mobility (6-minute gait cadence, speed, and distance, and 4-m gait speed) with free-living gait cadence from wearable accelerometers in predicting fall rates. Accelerometry data were collected with wrist-worn Actigraphs (GT9X) over 7 days in 432 community-dwelling older adults (aged 77.29 ± 5.46 years, 59.1% men, 80.2% White) participating in the Study to Understand Fall Reduction and Vitamin D in You. Falls were ascertained using monthly calendars, quarterly contacts, and ad hoc telephone reports. Accelerometry-based free-living gait cadence was estimated with the Adaptive Empirical Pattern Transformation algorithm.

resultsAcross all participants, free-living cadence was significantly related to fall rates; every 10 steps per minute higher cadence was associated with a 13.2% lower fall rate (p = .036). Clinic-based measures of mobility were not related to falls (p > .05). Among higher-functioning participants (cadence ≥100 steps/minute), every 10 steps per minute higher free-living cadence was associated with a 27.7% lower fall rate (p = .01). In participants with slow baseline gait (gait speed <0.8 m/s), all metrics were significantly associated with fall rates.

conclusionData collected from biosensors in the free-living environment may provide a more sensitive indicator of fall risk than in-clinic tests, especially among higher-functioning older adults who may be more responsive to intervention. CLINICAL

trial registrationNCT02166333.

Indexed as

GaitWearable Electronic DevicesAccelerometryAgedFemaleHumansIndependent LivingMaleWalkingWalking SpeedFall ratesRemote data collectionWalkingWearable devices

Identifiers

PMID35029661
PMCPMC10172982
OpenAlexW4206463238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.