Evidence map›Paper›PMID 35029329›Full record

ArticleCancer medicine2022

Trends in the incidence of head and neck cancer by subsite between 1993 and 2015 in Japan.

Daisuke Kawakita, Isao Oze, Shinichi Iwasaki, Tomohiro Matsuda, Keitaro Matsuo, Hidemi Ito

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. A Systematic Review of the Economic Burden of Proton Therapy in Head and Neck Cancer.Asian Pacific journal of cancer prevention : APJCP · 2023
    Pooled it
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  3. Incidence and survival of epithelial salivary glands cancer by tumor site and histology in Tarragona and Girona, Catalonia, Spain.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Daisuke KawakitaDivision of Cancer Epidemiology and Prevention, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.
Isao OzeDivision of Cancer Epidemiology and Prevention, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID 0000-0002-0762-1147
Shinichi IwasakiDepartment of Otorhinolaryngology, Head and Neck Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Tomohiro MatsudaDivision of International Collaborative Research, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Keitaro MatsuoDivision of Cancer Epidemiology and Prevention, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID 0000-0003-1761-6314
Hidemi ItoDivision of Cancer Information and Control, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID 0000-0002-8023-4581
Aichi Cancer Center · JPNagoya City University · JPNational Center for Global Health and Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTobacco use and alcohol consumption are still important risk factors for head and neck cancer (HNC) in developing countries, even though decreasing in tobacco prevalence. Recently, an increased incidence of oropharyngeal cancer due to human papilloma virus (HPV) infection has attracted attention in advanced countries, including the United States and Europe. However, few studies have evaluated trends in the incidence of HNC by subsite in Japan.

methodsAccordingly, we evaluated these trends in Japan using data from population-based cancer registries. We compiled population-based incidence data from the Monitoring of Cancer Incidence in Japan Project, based on data from 19 population-based cancer registries. Number of incident cases and age-standardized incidence rates of HNC were estimated by subsite, namely lip, oral cavity, salivary glands, nasopharynx, oropharynx, hypopharynx, larynx, nasal and paranasal cavity, middle ear and NOS. Trends in agestandardized incidence rates were characterized using the Joinpoint analysis.

resultsAmong both sexes, oral cavity cancer, salivary gland cancer, and oropharyngeal cancer showed an upward trend (oral cavity: annual percent change (APC) 1.2% for men and APC 1.9% for women; salivary gland: APC 2.2% for men and APC 3.1% for women; oropharynx: APC 5.0% for men and APC 7.6% for women). Additionally, hypopharyngeal cancer showed an upward trend for men (APC 4.1%), and nasopharyngeal cancer and laryngeal cancer showed a downward trend for men (nasopharynx: APC -2.7%; larynx: -1.1%).

conclusionsThese findings will assist in focusing on the individual prevention of HNC.

Indexed as

Head and Neck NeoplasmsNasopharyngeal NeoplasmsOropharyngeal NeoplasmsPapillomavirus InfectionsFemaleHumansIncidenceJapanMaleRegistriesUnited Statesage-standardized incidence rateannual percent changehead and neck cancersubsite

Identifiers

PMID35029329
PMCPMC8921930
OpenAlexW4205172382

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.