Evidence map›Paper›PMID 35029289›Full record

ArticleOncology reports2022

Zinc finger protein 384 enhances colorectal cancer metastasis by upregulating MMP2.

Zaihua Yan, Yu Zhou, Yang Yang, Chongpu Zeng, Peidong Li, Hongpeng Tian, Xuegui Tang, Guangjun Zhang

Open access · hybridAbstract read
In one paragraph

Article in Oncology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  15. Review
  16. The Roles of Zinc Finger Proteins in Colorectal Cancer.International journal of molecular sciences · 2023
    Review
  17. Article
  18. ZNF384-ZEB1 feedback loop regulates breast cancer metastasis.Molecular medicine (Cambridge, Mass.) · 2022
    Article
  19. ZNF384-Related Fusion Genes in Acute Lymphoblastic Leukemia.Cancer control : journal of the Moffitt Cancer Center
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zaihua Yan *Second Department of Gastrointestinal Surgery, The Affiliated Hospital of North Sichuan Medical College, North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Yu Zhou *Second Department of Gastrointestinal Surgery, The Affiliated Hospital of North Sichuan Medical College, North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Yang Yang *Department of Dermatology, Xining First People's Hospital, Xining, Qinghai 810000, P.R. China.
Chongpu ZengDepartment of General Surgery, Wangcang County People's Hospital, Guangyuan, Sichuan 628200, P.R. China.
Peidong LiSecond Department of Gastrointestinal Surgery, The Affiliated Hospital of North Sichuan Medical College, North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Hongpeng TianSecond Department of Gastrointestinal Surgery, The Affiliated Hospital of North Sichuan Medical College, North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Xuegui TangAnorectal Department of Integrated Traditional Chinese and Western Medicine, The Affiliated Hospital of North Sichuan Medical College, North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Guangjun ZhangSecond Department of Gastrointestinal Surgery, The Affiliated Hospital of North Sichuan Medical College, North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Affiliated Hospital of North Sichuan Medical College · CNQinghai No.3 People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc finger proteins (ZNFs) serve key roles in tumor formation and progression; however, the functions and underlying mechanisms of dysregulated ZNF384 in colorectal cancer (CRC) are yet to be fully elucidated. Therefore, the present study initially aimed to investigate the expression levels of ZNF384 in CRC samples. Moreover, lentiviral ZNF384 overexpression and ZNF384 knockdown models were established in CRC cells. Transwell, wound healing and

Indexed as

Cell Line, TumorCell ProliferationColorectal NeoplasmsGene Expression Regulation, NeoplasticHumansMatrix Metalloproteinase 2Neoplasm InvasivenessTrans-ActivatorsUp-RegulationZinc FingersMatrix Metalloproteinase 2MMP2 protein, humanTrans-ActivatorsZNF384 protein, humancolorectal cancerhypoxia‑inducible factor 1αinvasionmigrationMMP2zinc finger protein 384

Identifiers

PMID35029289
PMCPMC8771166
OpenAlexW4206215664

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.