Evidence map›Paper›PMID 35029272›Full record

ArticleOrganic & biomolecular chemistry2022

Radiosynthesis and evaluation of a fluorine-18 radiotracer [

Lin Qiu, Hao Jiang, Yanbo Yu, Jiwei Gu, Jinzhi Wang, Haiyang Zhao, Tianyu Huang, Robert J Gropler, Robyn S Klein, Joel S Perlmutter and 1 more

Open access · greenAbstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Automated production of radiotracer [Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Room Temperature Synthesis of Bioactive 1,2,4-Oxadiazoles.International journal of molecular sciences · 2023
    Review
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Lin QiuDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA. zhudetu@wustl.edu.ORCID 0000-0001-8823-4132
Hao JiangDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA. zhudetu@wustl.edu.
Yanbo YuDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA. zhudetu@wustl.edu.ORCID 0000-0002-6687-9850
Jiwei GuDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA. zhudetu@wustl.edu.
Jinzhi WangDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA. zhudetu@wustl.edu.
Haiyang ZhaoDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA. zhudetu@wustl.edu.
Tianyu HuangDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA. zhudetu@wustl.edu.
Robert J GroplerDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA. zhudetu@wustl.edu.
Robyn S KleinDepartment of Medicine, Washington University School of Medicine, Saint Louis, Missouri 63110, USA.
Joel S PerlmutterDepartments of Neuroscience, Washington University School of Medicine, Saint Louis, MO 63110, USA.
Zhude TuDepartment of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA. zhudetu@wustl.edu.ORCID 0000-0003-0325-835X
Washington University in St. Louis · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
Training/DisseminationP41EB025815 · NIBIB · WASHINGTON UNIVERSITY · PI Buck E. Rogers · 2018 to 2026
$12.7M
INVESTIGATIONS OF DEMENTIA IN PARKINSON DISEASER01NS075321 · NINDS · WASHINGTON UNIVERSITY · PI CAMPBELL, MEGHAN C, PERLMUTTER, JOEL SYNES · 2011 to 2021
$8.2M
PET SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 (S1PR1) RADIOTRACERS FOR MULTIPLE SCLEROSISR01NS103988 · NINDS · WASHINGTON UNIVERSITY · PI Tammie Lee Smith Benzinger, Zhude Tu · 2017 to 2026
$5.3M
PET PROBES FOR IMAGING THE VESICULAR ACETYLCHOLINE TRANSPORTERR01NS075527 · NINDS · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2011 to 2021
$4.9M
Neuroinflammatory Biomarkers for Nigrostriatal InjuryR01NS107281 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES · 2019 to 2023
$3.3M
Neuroimaging of PDE10AR01NS103957 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES, TU, ZHUDE · 2017 to 2021
$3.1M
Investigations of Dementia in Parkinson DiseaseRF1NS075321 · NINDS · WASHINGTON UNIVERSITY · PI CAMPBELL, MEGHAN C, PERLMUTTER, JOEL SYNES · 2023 to 2023
$2.3M
NCI NIH HHS P30 CA091842NIBIB NIH HHS P41 EB025815NINDS NIH HHS R01 NS075321NINDS NIH HHS R01 NS075527NINDS NIH HHS R01 NS103957NINDS NIH HHS R01 NS103988NINDS NIH HHS R01 NS107281NINDS NIH HHS RF1 NS075321
6 · The paper itself

Abstract

Assessment of sphingosine-1-phosphate receptor 1 (S1PR1) expression could be a unique tool to determine the neuroinflammatory status for central nervous system (CNS) disorders. Our preclinical results indicate that PET imaging with [

Indexed as

AnimalsBrainFemaleFluorine RadioisotopesHumansIsotope LabelingMacacaMaleOxadiazolesPositron-Emission TomographyRadiopharmaceuticalsRatsRats, Sprague-DawleySphingosine-1-Phosphate ReceptorsFluorine-18Fluorine RadioisotopesOxadiazolesRadiopharmaceuticalsS1PR1 protein, humanS1PR1 protein, ratSphingosine-1-Phosphate Receptors

Identifiers

PMID35029272
PMCPMC8970350
OpenAlexW4205297962

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.