Evidence map›Paper›PMID 35029129›Full record

ArticleEpigenomics2022

Navigating the hydroxymethylome: experimental biases and quality control tools for the tandem bisulfite and oxidative bisulfite Illumina microarrays.

Ze Zhang, Min Kyung Lee, Laurent Perreard, Karl T Kelsey, Brock C Christensen, Lucas A Salas

Open access · hybridAbstract read
In one paragraph

Article in Epigenomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ze ZhangDepartment of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, 03756 NH, USA.ORCID 0000-0001-9854-5823
Min Kyung LeeDepartment of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, 03756 NH, USA.ORCID 0000-0001-9558-4819
Laurent PerreardDepartment of Molecular & Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, 03756 NH, USA.
Karl T KelseyDepartment of Epidemiology, Department of Pathology & Laboratory Medicine, Brown University School of Public Health, Providence, 02912 RI, USA.ORCID 0000-0002-2302-1600
Brock C ChristensenDepartment of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, 03756 NH, USA.ORCID 0000-0003-3022-426X
Lucas A SalasDepartment of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, 03756 NH, USA.ORCID 0000-0002-2279-4097
Dartmouth College · USBrown University · US

Funding

Relation Between In-utero Vitamin D and Immune Function in Early Childhood P20GM104416 · NIGMS · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA · 2013 to 2022
$23.7M
Immune epigenetic biomarkers of survival in glioma epidemiologyR01CA207360 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WIENCKE, JOHN K. · 2017 to 2021
$3.8M
DNA-based Immune Phenotyping in HNSCC for Biomarkers of Response to ImmunotherapyR01CA253976 · NCI · BROWN UNIVERSITY · PI CHRISTENSEN, BROCK C, KELSEY, KARL TIMOTHY · 2021 to 2025
$3.3M
(PQ3) Immune epigenetic biomarkers of bladder cancer outcomesR01CA216265 · NCI · DARTMOUTH COLLEGE · PI CHRISTENSEN, BROCK CLARKE · 2017 to 2021
$2.9M
NCI NIH HHS R01 CA207360NCI NIH HHS R01 CA216265NCI NIH HHS R01 CA253976NIGMS NIH HHS P20 GM104416
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Oligonucleotide Array Sequence Analysis5-MethylcytosineBiasComputational BiologyDNA MethylationHumansQuality Control5-hydroxymethylcytosine5-Methylcytosinebisulfite conversionDNA hydroxymethylationDNA methylationepigeneticsInfinium HumanMethylation450K BeadChipInfinium MethylationEPIC BeadChipoxidative bisulfite conversion

Identifiers

PMID35029129
PMCPMC8914583
OpenAlexW4206760233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.