Evidence map›Paper›PMID 35028920›Full record

ReviewProbiotics and antimicrobial proteins2022

Antimutagenic Activity as a Criterion of Potential Probiotic Properties.

Evgeniya V Prazdnova, Maria S Mazanko, Vladimir A Chistyakov, Anna A Bogdanova, Aleksandr G Refeld, Evgeniya Y Kharchenko, Michael L Chikindas

Abstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Iranian journal of microbiology · 2026
    Article
  2. Lactobacilli and gut pH: features of correlation in model experiments.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  3. Review
  4. Review
  5. Repression ofMicroorganisms · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Evgeniya V PrazdnovaAcademy of Biology and Biotechnologies, Southern Federal University, Prospect Stachki, 194/1, Rostov-on-Don, Russia. prazdnova@sfedu.ru.ORCID 0000-0001-7823-9044
Maria S MazankoAcademy of Biology and Biotechnologies, Southern Federal University, Prospect Stachki, 194/1, Rostov-on-Don, Russia.
Vladimir A ChistyakovAcademy of Biology and Biotechnologies, Southern Federal University, Prospect Stachki, 194/1, Rostov-on-Don, Russia.
Anna A BogdanovaEvolutionary Biomedicine Laboratory, SCAMT Institute, ITMO University, Saint Petersburg, Russia.
Aleksandr G RefeldCell Biophysics Laboratory, SCAMT Institute, ITMO University, Saint Petersburg, Russia.
Evgeniya Y KharchenkoAcademy of Biology and Biotechnologies, Southern Federal University, Prospect Stachki, 194/1, Rostov-on-Don, Russia.
Michael L ChikindasCenter for Agrobiotechnology, Don State Technical University, Rostov-on-Don, Russia.
Southern Federal University · RUITMO University · RURutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antimutagenic activity of probiotic strains has been reported over several decades of studying the effects of probiotics. However, this activity is rarely considered an important criterion when choosing strains to produce probiotic preparations and functional food. Meanwhile, the association of antimutagenic activity with the prevention of oncological diseases, as well as with a decrease in the spread of resistant forms in the microbiota, indicates its importance for the selection of probiotics. Besides, an antimutagenic activity can be associated with probiotics' broader systemic effects, such as geroprotective activity. The main mechanisms of such effects are considered to be the binding of mutagens, the transformation of mutagens, and inhibition of the transformation of promutagens into antimutagens. Besides, we should consider the possibility of interaction of the microbiota with regulatory processes in eukaryotic cells, in particular, through the effect on mitochondria. This work aims to systematize data on the antimutagenic activity of probiotics and emphasize antimutagenic activity as a significant criterion for the selection of probiotic strains.

Indexed as

Antimutagenic AgentsMicrobiotaProbioticsMutagensAntimutagenic AgentsMutagensAntimutagenic agentsAntioxidantsBacillusBacteriaBbifidobacteriumLactobacillusProbiotics

Identifiers

PMID35028920
OpenAlexW4205820207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.