Evidence map›Paper›PMID 35028894›Full record

ArticleJournal of nephrology2022

Characteristics of outpatients referred for a first consultation with a nephrologist: impact of different guidelines.

Céline Schulz, Ziyad Messikh, Pascal Reboul, Sylvain Cariou, Pedram Ahmadpoor, Emilie Pambrun, Camelia Prelipcean, Florian Garo, Julien Prouvot, Pierre Delanaye and 1 more

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In one paragraph

Article in Journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Ten tips for kidney biopsy in cancer patients.Clinical kidney journal · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Green, Sustainable Nephrology: State of the Art Needs for Education and Implementation.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Céline SchulzService de Nephrologie, Dialyses Apherese, Hopital Universitaire de Nimes, Nimes, France.
Ziyad MessikhService de Nephrologie, Dialyses Apherese, Hopital Universitaire de Nimes, Nimes, France.
Pascal ReboulService de Nephrologie, Dialyses Apherese, Hopital Universitaire de Nimes, Nimes, France.
Sylvain CariouService de Nephrologie, Dialyses Apherese, Hopital Universitaire de Nimes, Nimes, France.
Pedram AhmadpoorService de Nephrologie, Dialyses Apherese, Hopital Universitaire de Nimes, Nimes, France.
Emilie PambrunService de Nephrologie, Dialyses Apherese, Hopital Universitaire de Nimes, Nimes, France.
Camelia PrelipceanService de Nephrologie, Dialyses Apherese, Hopital Universitaire de Nimes, Nimes, France.
Florian GaroService de Nephrologie, Dialyses Apherese, Hopital Universitaire de Nimes, Nimes, France.
Julien ProuvotService de Nephrologie, Dialyses Apherese, Hopital Universitaire de Nimes, Nimes, France.
Pierre DelanayeService de Nephrologie, Dialyses Apherese, Hopital Universitaire de Nimes, Nimes, France.
Olivier MoranneService de Nephrologie, Dialyses Apherese, Hopital Universitaire de Nimes, Nimes, France. olivier.moranne@chu-nimes.fr.ORCID http://orcid.org/0000-0002-3127-1415
Centre Hospitalier Universitaire de Nîmes · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic kidney disease (CKD) affects > 10% of the population but not all CKD patients require referral to a nephrologist. Various recommendations for referral to nephrologists are proposed worldwide. We examined the profile of French patients consulting a nephrologist for the first time and compared these characteristics with the recommendations of the International Kidney Disease: Improving Global Outcomes (KDIGO), the French "Haute Autorité de Santé" (HAS), and the Canadian Kidney Failure Risk Equation (KFRE).

methodsUniversity Hospital electronic medical records were used to study patients referred for consultation with a nephrologist for the first time from 2016 to 2018. Patient characteristics (age, sex, diabetic status, estimated glomerular filtration rate (eGFR) and urine protein-to-creatinine ratio (PCR), etiology reported by the nephrologist) and 1-year patient follow-up were analyzed and compared with the KDIGO, HAS and Canadian-KFRE recommendations for referral to a nephrologist. The stages were defined according to the KDIGO classification, based upon kidney function and proteinuria. 

resultsThe 1,547 included patients had a median age of 71 [61-79] years with 56% males and 37% with diabetes. The main nephropathies were vascular (40%) and glomerular (20%). The KDIGO classification revealed 30%, 47%, 19%, 4% stages G1-2 to G5, and 50%, 22%, 28% stages A1-A3, respectively. According to KDIGO, HAS and KFRE scores, nephrologist referral was indicated for 42%, 57% and 80% of patients respectively, with poor agreement between recommendations. Furthermore, we observed 890 (57%) patients with an eGFR> 30 ml/min and  a urine protein to creatinine ratio 0.5 g/g, mostly aged over 65 years (67%); 40% were diabetic, and 57% had a eGFR > 45 ml/min/1.73m

conclusionThese results underline the importance of better identifying patients for referral to a nephrologist and informing general practitioners. Other referral criteria (age and etiology of the nephropathy) are debatable.

Indexed as

Kidney Failure, ChronicRenal Insufficiency, ChronicAgedCanadaCreatinineFemaleGlomerular Filtration RateHumansMaleMiddle AgedNephrologistsOutpatientsReferral and ConsultationCreatinineCKDNephrologistOutpatientRecommendationsReferral

Identifiers

PMID35028894
OpenAlexW4205663571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.