SynthesisJournal of anesthesia2022
The impact of intraoperative blood pressure variability on the risk of postoperative adverse outcomes in non-cardiac surgery: a systematic review.
Synthesis in Journal of anesthesia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Effect of lidocaine on intraoperative blood pressure variability in patients undergoing major vascular surgery.BMC anesthesiology · 2024Trial
- In reply: association between intraoperative hypotension and postoperative ICU delirium: a retrospective observational study.Journal of anesthesia · 2026Article
- Effects of intraoperative blood pressure variability on development of postoperative acute kidney injury among Japanese.Perioperative medicine (London, England) · 2026Article
- Comments on "Association between intraoperative hypotension and postoperative ICU delirium: a retrospective observational study" by Ono et al.Journal of anesthesia · 2026Article
- Machine learning prediction and explanation of high intraoperative blood pressure variability for noncardiac surgery using preoperative factors.BMC cardiovascular disorders · 2025Observational
- Effects of erector spinae plane block on intraoperative blood pressure variability, blood loss, and postoperative pain in transforaminal lumbar interbody fusion.Scientific reports · 2025Article
- Relationship between intraoperative blood pressure variability and postoperative acute kidney injury in pediatric cardiac surgery.Pediatric nephrology (Berlin, Germany) · 2025Observational
- Association between intraoperative blood pressure variability and postoperative complications: a narrative review.Frontiers in cardiovascular medicine · 2025Review
- Remifentanil reduces post-induction hypotension compared to fentanyl in thoracoscopic esophagectomy: a retrospective cohort study.Frontiers in pharmacology · 2025Article
- Association of postoperative delirium with hypotension in critically ill patients after cardiac surgery: a prospective observational study.Journal of cardiothoracic surgery · 2024Observational
- Effects of Intra-operative Cardiopulmonary Variability On Post-operative Pulmonary Complications in Major Non-cardiac Surgery: A Retrospective Cohort Study.Journal of medical systems · 2024Article
- Perioperative systemic blood pressure parameters and clinical outcomes following 27g vitrectomy for diabetic tractional detachment repair.BMJ open ophthalmology · 2023Article
- Predictive Capacity of Beat-to-Beat Blood Pressure Variability for Cardioautonomic and Vascular Dysfunction in Early Metabolic Challenge.Frontiers in pharmacology · 2022Article
- Nexfin versus conventional oscillometric cuff for blood pressure monitoring during neuro-endovascular procedures.Brain circulationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hemodynamic stability during surgery seems to account for positive postoperative outcomes in patients. However, little is known about the impact of intraoperative blood pressure variability (IBPV) on the postoperative complications. The aim was to investigate whether IBPV is associated with the development of postoperative complications and what is the nature of this association. We conducted a systematic search in PubMed, Medical Subject Headings, Embase, Web of Science, SCOPUS, clinicaltrials.gov, and Cochrane Library on the 8th of April, 2021. We included studies that only focused on adults who underwent primarily elective, non-cardiac surgery in which intraoperative blood pressure variation was measured and analyzed in regard to postoperative, non-surgical complications. We identified 11 papers. The studies varied in terms of applied definitions of blood pressure variation, of which standard deviation and average real variability were the most commonly applied definitions. Among the studies, the most consistent analyzed outcome was a 30-day mortality. The studies presented highly heterogeneous results, even after taking into account only the studies of best quality. Both higher and lower IBPV were reported to be associated for postoperative complications. Based on a limited number of studies, IBPV does not seem to be a reliable indicator in predicting postoperative complications. Existing premises suggest that either higher or lower IBPV could contribute to postoperative complications. Taking into account the heterogeneity and quality of the studies, the conclusions may not be definitive.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.