ArticleEuropean radiology2022
Percutaneous image-guided cryoablation of spinal metastases: over 10-year experience in two academic centers.
Article in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Percutaneous cryoablation in the management of spinal metastases: a comprehensive systematic review and meta-analysis.Journal of neuro-oncology · 2025Pooled it
- ESR Essentials: percutaneous bone consolidation-practice recommendations by the European Society of Musculoskeletal Radiology.European radiology · 2025Guideline
- Personalizing Bone Tumor Ablation: Decision Models from the University Hospital of Strasbourg.Cardiovascular and interventional radiology · 2026Article
- Curative-Intent Cryoablation for Bone Metastases: Study Protocol for BOREALIS, a Prospective Multicentre Observational Investigation.Cardiovascular and interventional radiology · 2026Observational
- Image-guided percutaneous interventions for bone tumors around the knee.Skeletal radiology · 2026Review
- Clinical efficacy and safety of robot-assisted targeted co-ablation combined with vertebroplasty under local anesthesia for spinal metastases.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Ablative Techniques for the Management of Osseous Spine Metastases: A Narrative Review.Journal of clinical medicine · 2025Review
- Review of Bone Metastasis in Gynecologic Malignancies: Evaluation and Treatment.Current treatment options in oncology · 2025Review
- Review
- Percutaneous Vertebral Augmentation and Thermal Ablation in Patients with Spinal Metastases.Seminars in interventional radiology · 2024Review
- Spine metastases: thermal ablation and augmentation.Skeletal radiology · 2023Review
- Locoregional Thermal and Chemical Tumor Ablation: Review of Clinical Applications and Potential Opportunities for Use in Low- and Middle-Income Countries.JCO global oncology · 2023Review
- The New Ice Age of Musculoskeletal Intervention: Role of Percutaneous Cryoablation in Bone and Soft Tissue Tumors.Current oncology (Toronto, Ont.) · 2023Review
- [CT-guided local ablative interventions].Radiologie (Heidelberg, Germany) · 2023Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo report on safety and clinical effectiveness of cryoablation for the treatment of spinal metastases (SM) in patients needing pain palliation or local tumor control (LTC).
methodsAll consecutive patients with SM who underwent cryoablation from May 2008 to September 2020 in two academic centers were retrospectively identified and included in the present analysis. Patient characteristics, goal of treatment (curative/palliative), SM characteristics, procedural details, and clinical outcomes (pain relief; local tumor control [LTC]) were analyzed.
resultsThere were 74 patients (35 women; median age 61 years) accounting for 105 SM. Additional cementoplasty was used for 76 SM (76/105; 72.4%). There were 9 complications (out of 105 SM [8.5%]; 2 major and 7 minor) in 8 patients. Among the 64 (64/74; 86.5%) patients with painful SM, the mean Numerical Pain Rating Scale dropped from 6.8 ± 2.2 (range, 0-10) at the baseline to 4.1 ± 2.4 (range, 0-9; p < 0.0001) at 24 h, 2.5 ± 2.6 (range, 0-9; p < 0.0001) at 1 month, and 2.4 ± 2.5 (range, 0-9; p < 0.0001) at the last available follow-up (mean 14.7 ± 19.6 months; median 6). Thirty-four patients (34/64; 53.1%) were completely pain-free at the last follow-up. At mean 25.9 ± 21.2 months (median 16.5) of follow-up, LTC was achieved in 23/28 (82.1%) SM in 21 patients undergoing cryoablation with curative intent.
conclusionCryoablation of SM, often performed in combination with vertebral augmentation, is safe, achieves fast and sustained pain relief, and provides high rates of LTC at mean 2-year follow-up. KEY POINTS: •Cryoablation of spinal metastases is safe. •Cryoablation of spinal metastases allows rapid and sustained pain relief. •The mean 2-year rate of local tumor control after cryoablation of spinal metastases is 82.1%.
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