Evidence map›Paper›PMID 35028726›Full record

ArticleEuropean journal of pediatrics2022

A comparative study on the incidence of type 1 diabetes mellitus between children of North African migrants and Italian children in Emilia-Romagna region, Italy.

Giulio Maltoni, Maximiliano Zioutas, Marta Mosticchio, Lorenzo Iughetti, Barbara Predieri, Patrizia Bruzzi, Brunella Iovane, Pietro Lazzeroni, Vanna Graziani, Tosca Suprani and 10 more

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In one paragraph

Article in European journal of pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 10 institutions in 1 country.

Giulio MaltoniPediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, via Massarenti 11, 40138, Bologna, Italy. giulio.maltoni@aosp.bo.it.ORCID http://orcid.org/0000-0002-2526-5588
Maximiliano ZioutasPediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, via Massarenti 11, 40138, Bologna, Italy.
Marta MosticchioPediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, via Massarenti 11, 40138, Bologna, Italy.
Lorenzo IughettiPediatric Unit, Department of Medical and SurgicalSciences of the Mothers, Children and Adults, University of Modena and Reggio Emilia, 41124, Modena, Italy.
Barbara PredieriPediatric Unit, Department of Medical and SurgicalSciences of the Mothers, Children and Adults, University of Modena and Reggio Emilia, 41124, Modena, Italy.
Patrizia BruzziPediatric Unit, Department of Medical and SurgicalSciences of the Mothers, Children and Adults, University of Modena and Reggio Emilia, 41124, Modena, Italy.
Brunella IovaneCenter for Diabetes in Children and Adolescents, Department of Woman and Child Health, Parma University Hospital, Parma, Italy.
Pietro LazzeroniCenter for Diabetes in Children and Adolescents, Department of Woman and Child Health, Parma University Hospital, Parma, Italy.
Vanna GrazianiDepartment of Pediatrics, Santa Maria Delle Croci Hospital, Ravenna, Italy.
Tosca SupraniDepartment of Pediatrics, Bufalini Hospital, Cesena, Italy.
Sara MontiDepartment of Pediatrics, Bufalini Hospital, Cesena, Italy.
Maria E StreetDivision of Pediatric Endocrinology and Diabetology Pediatrics, Department of Mother and Child, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Anna LasagniDivision of Pediatric Endocrinology and Diabetology Pediatrics, Department of Mother and Child, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Francesca De LucaPediatrics Unit, Azienda Ospedaliero-Universitaria di Ferrara, 44124, Ferrara, Italy.
Francesca LibertucciPediatrics Unit, AUSL Romagna, 47921, Rimini, Italy.
Benedetta MainettiPediatrics Unit, Ospedale "G.B. Morgagni - L. Pierantoni", Forlì, Italy.
Sara RiboniDepartment of Pediatrics and Neonatology, Guglielmo da Saliceto Hospital, Cantone del Cristo 50, Piacenza, Italy.
Paola Sogno ValinDepartment of Pediatrics, Santa Maria Della Scaletta Hospital, Imola, Italy.
Andrea PessionPediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, via Massarenti 11, 40138, Bologna, Italy.
Stefano ZucchiniPediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, via Massarenti 11, 40138, Bologna, Italy.
Azienda USL di Bologna · ITUniversity of Modena and Reggio Emilia · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITOspedale “M. Bufalini” di Cesena · ITUniversity of Parma · ITArcispedale Sant'Anna · ITAzienda Unità Sanitaria Locale Della Romagna · ITGuglielmo da Saliceto Hospital · ITOspedale G.B. Morgagni - L.Pierantoni · ITOspedale "Santa Maria delle Croci" di Ravenna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last few decades, many studies have reported an increasing global incidence of type 1 diabetes. Studies on migrant populations have underlined the importance of both environmental and genetic factors.

aimsEvaluate the incidence of type 1 diabetes in North African vs Italian children aged 0-14 years from 1 January 2015, to 31st December 2018, in Emilia-Romagna region, Italy.

methodsClinical and epidemiological data about childhood onset type 1 diabetes in Emilia Romagna region were retrospectively collected by the regional centers of pediatric diabetology and matched using 3 different data sources.

results365 new cases were diagnosed. Total cumulative incidence was 15.4/100,000/year. North African cases showed a cumulative incidence of 53.8/100,000/year, statistically significant compared to cumulative incidence of the Italian cases alone 13.1/100,000/year (p value < 0.001). The annual incidence did not differ in the 4 years for both groups.  Conclusion: The incidence of type 1 diabetes in the pediatric age (0 14 years) was significantly higher in the North African population than in the Italian one, suggesting that a mix of genetic and environmental factors may have caused the increase in newly diagnosed cases. WHAT IS KNOWN: • The incidence of type 1 diabetes largely varies worldwide. • Study on immigrants helped to better understand the interplay role between genetics and environment. WHAT IS NEW: • This is the first study focused on the incidence of children and adolescents of North African migrants in Italy. • The incidence of children and adolescents of North African migrants in Emilia Romagna region, Italy, seems to be higher than that reported in the host countries, and, above all, than that reported in highest-incidence countries in Europe and in the world.

Indexed as

Diabetes Mellitus, Type 1Emigrants and ImmigrantsTransients and MigrantsAdolescentChildChild, PreschoolHumansIncidenceInfantInfant, NewbornItalyRetrospective StudiesAutoimmune diseasesChildhood diabetesDiabetic ketoacidosisType 1 diabetes epidemiologyType 1 diabetes incidence

Identifiers

PMID35028726
OpenAlexW4205244492

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.