ReviewFaculty reviews2021
Brain-body responses to chronic stress: a brief review.
Review in Faculty reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Chronic stress in relation to clinical burnout: an integrative scoping review of definitions and measurement approaches.Frontiers in psychology · 2025Pooled it
- Beyond neural oscillations: Stress-related aperiodic activity and aperiodic-oscillatory spectral covariation.iScience · 2026Article
- Integrated brain and body mechanisms underlying acute stress and trauma-related vulnerability.Neurobiology of stress · 2026Article
- Heightened risk of fatal police violence in and around reservations for American Indian/Alaska Native peoples in the United States.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Mental Health Experiences and Challenges Among Individuals with Myasthenia Gravis: Insights from Patient-Centered, Qualitative Analyses.Advances in therapy · 2025Review
- Echoes of stress: From molecular whispers to social thunderstorms.Neurobiology of stress · 2025Review
- Combined Effects of Environmental and Lifestyle Exposures on Liver Health: The Mediating Role of Allostatic Load.Toxics · 2025Article
- The Consequence of the Cape: A Mixed-Methods Inquiry into the Sociocultural Stressors Impacting Black Women's Health.Journal of racial and ethnic health disparities · 2025Article
- Breathwork for Chronic Stress and Mental Health: Does Choosing a Specific Technique Matter?Medical sciences (Basel, Switzerland) · 2025Review
- Thiamine Compounds Alleviate Oxidative Stress, Over-Expression of Pro-Inflammatory Markers and Behavioral Abnormalities in a Mouse Predation Model of PTSD.International journal of molecular sciences · 2025Article
- Cardiovascular Disease and Cancer: A Dangerous Liaison.Arteriosclerosis, thrombosis, and vascular biology · 2025Review
- Joint Effects of Lifestyle Habits and Heavy Metals Exposure on Chronic Stress Among U.S. Adults: Insights from NHANES 2017-2018.Journal of xenobiotics · 2025Article
- Child Maltreatment Characteristics and Adult Physical Multimorbidity in Germany.JAMA network open · 2025Article
- Systematic interventions based on the stress-induced situation, affective, bodily, and cognitive reactions framework to mitigate psychological distress in lung cancer patients post-thoracoscopic surgery: a randomized clinical trial.Frontiers in psychology · 2025Article
- [Loneliness in times of global polycrises].Der Nervenarzt · 2024Review
- Article
- GLUT1-mediated microglial proinflammatory activation contributes to the development of stress-induced spatial learning and memory dysfunction in mice.Cell & bioscience · 2024Article
- Folie et Société: eroding the body-mind relationship via dysfunctional paternalistic systems.Frontiers in psychology · 2024Article
- Chronic Stress as a Risk Factor for Type 2 Diabetes: Endocrine, Metabolic, and Immune Implications.Endocrine, metabolic & immune disorders drug targets · 2024Review
- A revitalized biopsychosocial model: core theory, research paradigms, and clinical implications.Psychological medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In order to survive and thrive, organisms must adapt to constantly changing environmental pressures. When there are significant shifts in the environment, the brain and body engage a set of physiological and behavioral countermeasures collectively known as the "stress response". These responses, which include changes at the cellular, systems, and organismal level, are geared toward protecting homeostasis and adapting physiological operating parameters so as to enable the organism to overcome short-term challenges. It is the shift of these well-organized acute responses to dysregulated chronic responses that leads to pathologies. In a sense, the protective measures become destructive, causing the myriad health problems that are associated with chronic stress. To further complicate the situation, these challenges need not be purely physical in nature. Indeed, psychosocial stressors such as ruminating about challenges at work, resource insecurity, and unstable social environments can engage the very same emergency threat systems and eventually lead to the same types of pathologies that sometimes are described as "burnout" in humans. This short review focuses on very recent empirical work exploring the effects of chronic stress on key brain circuits, metabolism and metabolic function, and immune function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.